Fig 1: APOH and MGAM expression in the colonic mucosa. Tissue sections from patients with CD or BD stained with antibodies against APOH (A) or MGAM (B). The selected areas denoted by white boxes in left panels (original magnification, 100 ×) are enlarged in the right panels (200 ×). Scale bar, 200 µm.
Fig 2: Serum APOH and MGAM protein expression detected using ELISA in intestinal BD patients (A) and CD patients (B). Results are mean ± SEM; ***p < 0.001. n = 20 patients per each group.
Fig 3: MGAM and APOH characterization in human colon mucosal proteomes. (A) Significant biological pathways enriched among 3,266 proteins identified by TMT are represented as bar graphs (p < 0.05) with the MGAM-containing categories highlighted in red. Venn diagrams showing numbers of MGAM-and APOH-containing categories classified by cellular compartment (B), molecular function (C), and biological process (D) based on functional annotation with gene ontology (GO) analysis.
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