Description
Product Characteristics: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Cellular Localization: Nucleus
Target Information: Associates with Polycomb group (PcG) multiprotein complexes\, the complex class is required to maintain the transcriptionally repressive state of some genes (By similarity)