Description
Product Characteristics:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the Kr_ppel C2H2-type zinc-finger protein family, ZNF323 (zinc finger protein 323) is a 406 amino acid protein containing six C2H2-type zinc fingers and one SCAN box domain. Specifically, C2H2-type zinc fingers function to bind DNA, while SCAN box domains are thought to participate in protein-protein interactions. Therefore, it is probable that ZNF323 functions as a transcription factor. With highest expression in kidney, liver and lung and weaker expression in brain, heart, intestine, muscle, cholecyst and pancreas, ZNF323 is localized to the nucleus. It is also suggested that ZNF323 may play a role in the development of multiple embryonic organs.
Subcellular location: Nucleus
Synonyms: dJ874C20, OTTHUMP00000016202, zinc finger and SCAN domain containing 31, zinc finger protein 310 pseudogene, Zinc finger protein 323, ZN323_HUMAN, ZNF20-Lp, ZNF310P, ZNF323, ZSCAN31.
Target Information: This gene encodes a protein containing multiple C2H2-type zinc finger motifs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]