Description
Product Characteristics:
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity).
Subcellular location: Nucleus
Synonyms: FUP1, BTB/POZ domain-containing protein 7, BTBD7, KIAA1525
Target Information: Please see product details or send an inquiry to antibodies-online for additional target information