Fig 1: NET-prism application on polymerase-bound transcription factors. (a) Metaplot profiles and heatmaps over protein-coding genes (n = 4,314) for polymerase associated elongation (Spt6, Ssrp1) and initiation (TFIID, Med14) factors. A 10-bp smoothing window has been applied. Blue = Sense transcription, Red = Anti-sense transcription. (b) RNA Pol II interrogation of all NET-seq/prism libraries over a single gene (Srsf6). (c) Cumulative distribution of Pol II travelling ratio as assessed by NET-prism.