Fig 1: cmRNA mediated expression of different kinds of proteins in vitro and in vivo(A) Images show the bioluminescence of firefly luciferase at 6 h, 24 h, and 9 days after intramuscular injection of 10 µg of the LNP-cmRNA complex. (B) Detection of membrane protein IL-15 CD8a and IL-15 GPI expression by FACS. (C) ELISA detection of the secreted form of RBD antigen in the culture supernatant of 293T cells at 24 h post transfection with 0.5 µg of cmRNA, and in mouse serum at 24 h post intramuscular injection with 10 µg of LNP-cmRNA complex. **p < 0.01, ****p < 0.0001.