GoInVivo™ Purified Bulk Antibodies from BioLegend

Product Specs
ItemGoInVivo™ Purified Bulk Antibodies
CompanyBioLegend
Price Supplier Page View Company Product Page
Catalog NumberGoInVivo
ReactivityVaries
ApplicationsVaries
Conjugate/TagUnconjugated
ClonalityMonoclonal

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) The VIPR2-selective antagonist KS-133 changes macrophage polarization and exerts potent anti-tumor effects as a single agent and in combination with an anti-PD-1 antibodyPLOS ONEJuly 5, 2023Kotaro Sakamoto, Wararat Kittikulsuth, Eijiro Miyako, Akumwami Steeve, Rika Ishimura, Shinsaku Nakagawa, Yukio Ago, Akira Nishiyamaevery 3 days to tumor-bearing mice for 3 weeks. For anti-PD-1 monotherapy or combination treatment, GoInVivo Purified anti-mouse PD-1 (9.98 mg/mL) (CD279, Cat. #114114, BioLegend, San Diego, CA, USA) was diluted

(2) Bioactive fatty acid analog-derived hybrid nanoparticles confer antibody-independent chemo-immunotherapy against carcinomaJournal of NanobiotechnologyJune 8, 2023Xi Tan, Chenhui Wang, Hong Zhou, Shuting Zhang, Xuhan Liu, Xiangliang Yang, Wei LiuCamptothecin (CPT) and irinotecan hydrochloride (CPT-11) were obtained from Aladdin (Shanghai, China). GoInVivo™ purified anti-mouse PD-L1 antibody (αPD-L1, clone: 10F.9G2) was purchased from BioLegend Inc (San Diego,

(3) Biosynthetic neoantigen displayed on bacteria derived vesicles elicit systemic antitumour immunityJournal of Extracellular VesiclesDecember 5, 2022Fanqiang Meng, Liyan Li, Zhirang Zhang, Zhongda Lin, Jinxie Zhang, Xiao Song, Tianyuan Xue, Chenyang Xing, Xin Liang, Xudong ZhangGel‐Mutation‐M33‐M47 BDVs (150 μl, 25 μg BDVs and 20 ng/ml GM‐CSF, #4), aPD‐1 (anti‐PD‐1 antibody, GoInVivo Purified anti‐mouse CD279 (PD‐1), Biolegend, 114115, 2.5 mg/kg, #5) and Gel‐Mutation‐M33‐M47 BDVs +

(4) Depletion of tumor associated macrophages enhances local and systemic platelet-mediated anti-PD-1 delivery for post-surgery tumor recurrence treatmentNature CommunicationsDecember 1, 2022Zhaoting Li, Yingyue Ding, Jun Liu, Jianxin Wang, Fanyi Mo, Yixin Wang, Ting-Jing Chen-Mayfield, Paul M. Sondel, Seungpyo Hong, Quanyin Huconfluence. The antibodies used in this study were summarized as follows (company, clone, category number): GoInVivo Purified anti-mouse CD279 (PD-1) (BioLegend, RMP1-14, 114114), Fluorescein isothiocyanate (FITC)-anti-mouse

(5) In vitro and in vivo functions of T cells produced in complemented thymi of chimeric mice generated by blastocyst complementationScientific ReportsDecember 1, 2022Kazuto Yamazaki et al.MC38 cells as mentioned above (day 0). They were then injected with control IgG (50 μg/100 μL/head; GoInVivo Purified Rat IgG2b, κ, clone RTK4530, catalog no. 400666, BioLegend) (n = 5 for B6; n = 4 for chimeras)

(6) Enhancing Gasdermin-induced tumor pyroptosis through preventing ESCRT-dependent cell membrane repair augments antitumor immune responseNature CommunicationsOctober 24, 2022Zhaoting Li, Fanyi Mo, Yixin Wang, Wen Li, Yu Chen, Jun Liu, Ting-Jing Chen-Mayfield, Quanyin Huhumidity. The antibodies used in this study were summarized as follows (company, clone, category number): GoInVivo Purified anti-mouse CD279 (PD-1) (BioLegend, RMP1-14, 114114), Fluorescein isothiocyanate (FITC)-anti-mouse

(7) Na(+)/H(+)-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cellsCancer Res CommunAugust 1, 2022Gong YY, Shao H, Li Y, Brafford P, Stine ZE, Sun J, Felsher DW, Orange JS, Albelda SM, Dang CV.the effect of systemic buffering on the efficacy of ICB, mice were treated with either 12 mg/kg of GoInVivo purified anti-mouse CD279 (PD1) antibody (BioLegend, 135235) or isotype control antibody (BioLegend,

(8) Glycoengineered anti-CD39 promotes anticancer responses by depleting suppressive cells and inhibiting angiogenesis in tumor modelsJournal of Clinical InvestigationJuly 1, 2022Haohai Zhang, Lili Feng, Paola de Andrade Mello, Changchuin Mao, Richard Near, Eva Csizmadia, Leo Li-Ying Chan, Keiichi Enjyoji, Wenda Gao, Haitao Zhao, et al.4% Ultra-Low IgG serum (Thermo Fisher Scientific) and incubated with serially diluted mAbs (CTRL-m1, GoInVivo Purified Mouse IgG1κ control antibody, BioLegend), WT 5F2-m1, WT 5F2-m2c, and Afuc 5F2-m2c αmCD39 antibodies)

(9) The K-Ras(G12D)-inhibitory peptide KS-58 suppresses growth of murine CT26 colorectal cancer cell-derived tumorsScientific reportsMay 17, 2022Sakamoto K, Lin B, Nunomura K, Izawa T, Nakagawa S.group, n = 3 mice per satellite group) (Fig. 1B). For anti-PD-1 monotherapy or combination treatment, GoInVivo Purified anti-mouse PD-1 (CD279, Cat.#114114, BioLegend, San Diego, CA, USA) was dissolved in PBS and

(10) PD-L1 signaling selectively regulates T cell lymphatic transendothelial migrationNature communicationsApril 21, 2022Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, Lape IT, Paluskievicz C, Hippen KL, Lee Y, et al.polyacrylamide desalting columns (#43426). All kits were from Thermo Fisher Scientific, Inc. (Waltham, MA,). GoInVivo purified anti-human PD-1 (EH12.2H7), human PD-L1 (29E.2A3), and human PD-L1 (MIH3) were purchased from

(11) Flow cytometric analysis of CD4+ T cell reactivation following anti-PD1 immunotherapy in a transgenic mouse modelSTAR ProtocolsMarch 18, 2022Lozan Sheriff, David BendingAB_10696422 "Rat anti-mouse OX40 APC (clone OX-86, 1 in 200 dilution)",BioLegend,Cat# 119413; RRID: AB_2561723 GoInVivo Purified anti-mouse PD-1 (clone 29F.1A12),BioLegend,Cat# 135233; RRID: AB_2616834 InVivo Mab rat anti-mouse

(12) Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strengthImmunityNovember 9, 2021Thomas A.E. Elliot, Emma K. Jennings, David A.J. Lecky, Natasha Thawait, Adriana Flores-Langarica, Alastair Copland, Kendle M. Maslowski, David C. Wraith, David Bendingsupernatant,Prof. Anne Cooke (University of Cambridge),Gift from Prof. Anne Cooke (University of Cambridge GoInVivo Purified anti-mouse Lag3 (clone C97BW),BioLegend,Cat# 125216; RRID: AB_2566284 GoInVivo Purified anti-mouse

(13) VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effectsJournal for ImmunoTherapy of CancerNovember 9, 2021Miriam Bazan-Peregrino et al.randomized and treated as described in the figure legend (figure 2C). Anti-PD-L1 antibody was purchased from GoInVivo purified anti-mouse CD274, B7-H1, Ref: 124329, Biolegend. Tumor volume, body weight, and clinical signs

(14) A Novel Oral Arginase 1/2 Inhibitor Enhances the Antitumor Effect of PD-1 Inhibition in Murine Experimental Gliomas by Altering the Immunosuppressive EnvironmentFrontiers in OncologyAugust 24, 2021Paulina Pilanc et al.by oral gavage at 50 mg/kg twice a day from day 1 after implantation. Anti-PD-1 antibody (Biolegend, GoInVivo™ Purified anti-mouse CD279) was injected intraperitoneally (i.p.) at a dose of 2.5 mg/kg on days 8,

(15) Anti-tumor efficacy of a combination therapy with PD-L1 targeted alpha therapy and adoptive cell transfer of PD-1 deficient melanoma-specific human T-lymphocytesOncoImmunologyJuly 9, 2021L Marotte et al.Invivogen) to check the absence of mycoplasma contamination. Radiolabeling of anti-human-PD-L1 mAb The GoInVivo™ purified anti-human PD-L1 mouse mAb (antiPD-L1 mAb) was purchased from Biolegend (San Diego, CA, USA).

(16) PLGA-particle vaccine carrying TLR3/RIG-I ligand Riboxxim synergizes with immune checkpoint blockade for effective anti-cancer immunotherapyNature communicationsMay 18, 2021Koerner J, Horvath D, Herrmann VL, MacKerracher A, Gander B, Yagita H, Rohayem J, Groettrup M.response (day 6 post-vaccination). Immune checkpoint blockade was achieved by multiple i.p. injections of GoInVivo™ purified anti-mouse CD152 (clone 9H10, #106205, BioLegend) with a cumulative dose of 250 µg anti-CTLA-4

(17) Concentrated Secretome of Adipose Stromal Cells Limits Influenza A Virus-Induced Lung Injury in MiceCellsMarch 24, 2021Bogatcheva NV, Coleman ME.range 0.2–5.0 mg/kg body weight (Dr. Coleman, unpublished observations)). Anti-mouse PDL1 antibody (GoInVivo clone 10F.9G2, Biolegend, San Diego, CA, USA) were administered SQ (8 mg/kg) at Day 6 and Day 8 post-infection.

(18) Anti-Tumor Efficacy of PD-L1 Targeted Alpha-Particle Therapy in a Human Melanoma Xenograft ModelCancers (Basel)March 12, 2021Marisa Capitao et al.purified anti-human PD-L1 mouse mAb (anti-hPD-L1 mAb), PEconjugated anti-hPD-L1 mAb (clone 29E.2A3), GoInVivo™ purified mouse IgG2bκ isotype control, and PE-conjugated mouse IgG2bκ isotype control (clone MPC-11)

(19) TAS0314, a novel multi-epitope long peptide vaccine, showed synergistic antitumor immunity with PD-1/PD-L1 blockade in HLA-A*2402 miceScientific ReportsDecember 1, 2020Yuki Tanaka et al.purified anti-HLA-ABC mAb (clone: w6/32), GoInVivo purified anti-mouse CD274 (PD-L1) mAb (clone: 10F.9G2), GoInVivo purified rat IgG2b, κ Isotype Ctrl Antibody (clone: RTK4530), and purified mouse IgG2a, κ Isotype Ctrl

(20) Microneedles loaded with anti-PD-1–cisplatin nanoparticles for synergistic cancer immuno-chemotherapyNanoscaleSeptember 28, 2020Xinmiao Lan et al.salt)), and cholesterol were obtained from Avanti Polar Lipids (Alabaster, AL, USA). The aPD-1 antibody (GoInVivo™ Purified anti-mouse CD279, BioLegend, San Diego, CA, USA) was purchased from BioLegend. 4.2 Cell line FaDu

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GoInVivo™ from BioLegend

Immune Checkpoints

Graph of Functional Assay - Anti-human PD-1 inhibits the binding of PD-L1

GoInVivo™ Purified Bulk Antibodies from BioLegend

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GoInVivo™ Purified Bulk Antibodies from BioLegend

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