Anti-KMT6 / EZH2 (phospho S21) antibody ab84989 from Abcam

Product Specs
ItemAnti-KMT6 / EZH2 (phospho S21) antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab84989
Antibody TypePrimary
Quantity100 UL
IsotypeIgG
Conjugate/TagUnconjugated
ApplicationsImmunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
ClonalityPolyclonal
HostRabbit
ModificationsPhospho-S21
Research AreaEpigenetics
Gene Nameezh2
ReactivityHuman, Mouse
TargetKMT6 / EZH2

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) GSK3β palmitoylation mediated by ZDHHC4 promotes tumorigenicity of glioblastoma stem cells in temozolomide-resistant glioblastoma through the EZH2-STAT3 axisOncogenesisMay 23, 2022Zhao C, Yu H, Fan X, Niu W, Fan J, Sun S, Gong M, Zhao B, Fang Z, Chen X.Proteintech (Wuhan, China). ZDHHC4 (ab235369), p-GSK3α + β (Y216 + Y279) (ab68476), and p-EZH2 (S21) (ab84989) were obtained from Abcam. Antibodies against FLAG (F1804) were purchased from Sigma–Aldrich. Methyl

(2) The Different Temozolomide Effects on Tumorigenesis Mechanisms of Pediatric Glioblastoma PBT24 and SF8628 Cell Tumor in CAM Model and on Cells In VitroInternational Journal of Molecular SciencesFebruary 11, 2022Eligija Damanskienė, Ingrida Balnytė, Angelija Valančiūtė, Marta Maria Alonso, Aidanas Preikšaitis, Donatas Stakišaitisantibodies to PCNA (PC10, Thermo Fisher Scientific, Branchburg, NJ, USA) and KMT6/EZH2 (phospho S21, ab84989, Abcam, Cambridge, UK) were used to detect PCNA and EZH2 positively stained tumor cells. Thin CAM sections

(3) The Effectiveness of Dichloroacetate on Human Glioblastoma Xenograft Growth Depends on Na+ and Mg2+ CationsDose-ResponseFebruary 27, 2021Donatas Stakišaitis, Eligija Damanskienė, Rūta Curkūnavičiūtė, Milda Juknevičienė, Marta Maria Alonso, Angelija Valančiūtė, Saulius Ročka, Ingrida BalnytėPrimary antibodies to the PCNA (PC10, Thermo Fisher Scientific, USA) and the KMT6/EZH2 (phospho S21, ab84989, Abcam, UK) were used to detect PCNA- and EZH2-positively stained tumor cells. Thin CAM sections of

(4) Association of axillary node status with clinicopathological characteristics and expression of EZH2 and CD44 in primary breast ductal carcinomaPakistan Journal of Medical SciencesNovember 25, 2020Miodrag Djordjevic, Aleksandar Karanikolic, Ljubinka Velickovic, Maja Milentijevicimmunohistochemistry on thin sections (4 μm) of tissue slides to examine the expression of EZH2 (clone ab84989, Abcam, 1/250 dilution), and CD44 (Dako, 1:50 dilution). The sections were cut, dried, deparaffinized,

(5) Mechanisms by Which Membrane and Nuclear ER Alpha Inhibit Adipogenesis in Cells Isolated From Female MiceEndocrinologyNovember 1, 2020Ahluwalia A, Hoa N, Ge L, Blumberg B, Levin ER.ChIP Santa Cruz), Ezh2 (1:500, 5246S, Cell Signaling Technology), pEZH2/KMT6 (phospho S21) (1:250, ab84989, Abcam), GATA3 (1:500, M00593, Boster Biological Technology), tri-methyl histone H3 (lysine 27) (1:250,

(6) Mesenchymal stem cell-derived exosomal microRNA-133b suppresses glioma progression via Wnt/β-catenin signaling pathway by targeting EZH2Stem Cell Research & TherapyDecember 1, 2019Haiyang Xu, Guifang Zhao, Yu Zhang, Hong Jiang, Weiyao Wang, Donghai Zhao, Jin Hong, Hongquan Yu, Ling Qitissues were incubated with the primary antibody, rabbit anti-human EZH2 (dilution ratio of 1: 200, ab84989, Abcam Inc., Cambridge, MA, USA) at 4 °C overnight, and then with the goat anti-rabbit immunoglobulin

(7) Sustained NF-κB-STAT3 signaling promotes resistance to Smac mimetics in Glioma stem-like cells but creates a vulnerability to EZH2 inhibitionCell death discoveryJanuary 1, 2019da Hora CC, Pinkham K, Carvalho L, Zinter M, Tabet E, Nakano I, Tannous BA, Badr CE.Phospho-AKT (Ser473; 9271), and β-Actin (3700) (Cell Signaling Technology); Anti-KMT6/EZH2 (phospho S21; ab84989) (Abcam); sheep anti-mouse IgG-HRP, donkey antirabbit IgG-HRP (Amersham Pharmacia Biotech). NF-κB reporter

(8) Sodium Valproate Inhibits Small Cell Lung Cancer Tumor Growth on the Chicken Embryo Chorioallantoic Membrane and Reduces the p53 and EZH2 ExpressionDose-ResponseApril 26, 2018Lina Šlekienė, Donatas Stakišaitis, Ingrida Balnytė, Angelija Valančiūtėclone240, and CBL404; Millipore, Darmstadt, Germany), rabbit polyclonal anti-KMT6/EZH2 (phospho S21,and ab84989; Abcam, Cambridge, UK), the E-cadherin monoclonal mouse antibody Ab-4 (1:50; clone: NCH-38; NeoMarkers,

(9) DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 miceCell Death & DiseaseMarch 1, 2018Shijie Zheng, Lirong Xiao, Yu Liu, Yujiao Wang, Lin Cheng, Junjun Zhang, Naihong Yan, Danian ChenEzh2 (1:1000, Cell Signaling Technology, 3147, Beverly, MA, USA), Phospho-Ezh2 (Ser21) (1:200, Abcam, ab84989, Cambridge, MA), H3K27me3 (1:1000, Cell Signaling Technology, Beverly, 9733, MA, USA), H3K9me3 (1:500,

(10) The Effect of Sodium Valproate on the Glioblastoma U87 Cell Line Tumor Development on the Chicken Embryo Chorioallantoic Membrane and on EZH2 and p53 ExpressionBioMed Research InternationalMay 31, 2017Dovilė Kavaliauskaitė, Donatas Stakišaitis, Justė Martinkutė, Lina Šlekienė, Arūnas Kazlauskas, Ingrida Balnytė, Vaiva Lesauskaitė, Angelija Valančiūtėstandard deparaffinization and rehydration techniques. The polyclonal anti-KMT6/EZH2 (phospho S21, ab84989, Abcam) and monoclonal anti-p53 (aa 211-220, clone240, CBL404, Millipore) antibodies were used as the primary

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Anti-KMT6 / EZH2 (phospho S21) antibody from Abcam

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Anti-KMT6 / EZH2 (phospho S21) antibody from Abcam

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