MyBioSource.com's Heparin Cofactor II Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, and Immunohistochemistry. The Heparin Cofactor II Antibody was generated using heparin cofactor II, and SERPIND1 as the antigen and it reacts with Human.
Description
Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.Blinder M.A., Biochemistry 27:752-759(1988).Herzog R., Biochemistry 30:1350-1357(1991).Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004)