Fig 2: A The difference in AAAS-v1 and AAAS-v2 transcript levels in the adrenal gland of the patient with Allgrove diesease (Pt) and two age-matched controls (CTR). B SCARB1 transcript analysis by RT-PCR in cortical adrenal gland of patient (Pt) and controls (CTR). C MiRNA-455 e miRNA-125a concentrations in cortical adrenal gland. Both miRNAs are significantly decreased in patient

Fig 3: A Reduction of Aladin protein amount in total lysate of patient’s cortical adrenal gland (Pt). B Reduction of Aladin protein in membrane fraction from patient’s cortical adrenal gland with a slight increasing in patient’s cytoplasmic fraction. C Reduction in P-PKA concentration in cortical adrenal gland from patient compared to two controls (CTR). D Increase of P-PKA protein in cytosolic fraction from patient cortical adrenal gland compared to controls and not significative reduction in P-PKA protein amount in patient’s nuclear fraction