Fig 1: Immunohistochemical analysis of hyperplastic FJ synovial tissue. (A) Immunohistochemical analysis of ANGPTL2 in the FJ synovial tissues of five patients who underwent surgery for lumbar degenerative diseases. (B) Immunohistochemistry for vimentin, CD68, CD15, and CD45 in the FJ synovial samples. (C) Double immunofluorescence staining for ANGPTL2 and vimentin (upper) or ANGPTL2 and CD68 (lower). Nuclei were stained with DAPI. (D) Immunohistochemistry for IL-6. Scale bars in each panel represent 50 μm. FJ, facet joint; ANGPTL2, angiopoietin-like protein 2; DAPI, 4',6'-diamidino-2-phenylindole; IL-6, interleukin-6.
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