Anti-INPP4B antibody [EPR3108Y] ab81269 from Abcam

Product Specs
ItemAnti-INPP4B antibody [EPR3108Y]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab81269
ApplicationsFlow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Flow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Flow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
IsotypeIgG
Quantity10 UL, 40 UL, 100 UL
Conjugate/TagUnconjugated
HostRabbit
ClonalityMonoclonal
CloneEPR3108Y
Gene NameINPP4B
ReactivityHuman
TargetINPP4B
Antibody TypePrimary

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) NanoString Digital Molecular Profiling of Protein and microRNA in RhabdomyosarcomaCancers (Basel)January 21, 2022Atif A. Ahmed, Midhat S. Farooqi, Sultan S. Habeebu, Elizabeth Gonzalez, Terrie G. Flatt, Ashley L. Wilson, Frederic G. Barrimmunohistochemistry for INPP4B was performed on each case with a Leica Bond instrument. A monoclonal antibody (ab81269 from Abcam, Cambridge, MA, USA) that detects the N-terminal of human INPP4B was used in 1:50 dilution.

(2) Expression and functional characterization of INPP4B in gallbladder cancer patients and gallbladder cancer cellsBMC CancerDecember 1, 2021Youliang Wu, Delong Meng, Xin Xu, Junjun Bao, Yexiang You, Yanjun Sun, Yongxiang Li, Dengqun Sun[21, 22]. The tissue sections were incubated with a primary monoclonal antibody against INPP4B (Abcam, ab81269, 1:50), while negative controls were incubated with normal rabbit IgG (Beyotime Institute of Biotechnology,

(3) Estrogen receptor β regulates AKT activity through up-regulation of INPP4B and inhibits migration of prostate cancer cell line PC-3Proceedings of the National Academy of SciencesOctober 20, 2020Surendra Chaurasiya, Wanfu Wu, Anders M. Strom, Margaret Warner, Jan-Åke Gustafssonbiotin. Sections were then incubated with anti-ERβ (1:100; made in our laboratory) or Anti-INPP4B (1:50; ab81269, Abcam) at 4 °C for overnight. After washing, sections were incubated with anti-chicken secondary antibody

(4) The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast CancerCancer discoveryAugust 1, 2020Liu H, Paddock MN, Wang H, Murphy CJ, Geck RC, Navarro AJ, Wulf GM, Elemento O, Haucke V, Cantley LC, et al.PRAS40 (#2691), Vinculin (#13901). Other antibodies used in this paper are as follows: INPP4B (Abcam, Ab81269), beta-actin (Sigma, A2228). Cell lines: MCF10A and MDA-MB-231cells were obtained from the American

(5) Retracted Article: LncRNA ZEB2-AS1 regulates the drug resistance of acute myeloid leukemia via the miR-142-3p/INPP4B axisRSC AdvancesNovember 27, 2019Kai Wang, Jing Dai, Tao Liu, Qiong Wang, Yingxu Pang(ab185002, Abcam, Cambridge, MA, USA), Bax (ab32503, Abcam), cleaved-caspase-3 (ab2302, Abcam), INPP4B (ab81269, Abcam) or GAPDH (ab37168, Abcam) overnight at 4 °C, and then incubated with HRP combined secondary

(6) Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast CancerInternational Journal of Biological SciencesMarch 9, 2019Hongtao Wang et al.was purchased from Santa Cruz Biotechnology (Santa Cruz, CA). Tuberin (ab32554,1:1000) and INPP4B (ab81269, 1:1000) were purchased from Abcam (Cambridge, UK). Western blot assay Cell lysates were harvested

(7) INPP4B As A Prognostic And Diagnostic Marker Regulates Cell Growth Of Pancreatic Cancer Via Activating AKTOncoTargets and therapyJanuary 1, 2019Zhai S, Liu Y, Lu X, Qian H, Tang X, Cheng X, Wang Y, Shi Y, Deng X.4-μm sections. The sections were incubated with primary antibody against INPP4B (rabbit monoclonal; ab81269, 1:500; Abcam, USA). Negative controls were incubated without primary antibody. After the slides were

(8) Survival of pancreatic cancer cells lacking KRAS functionNature CommunicationsDecember 1, 2017Mandar Deepak Muzumdar, Pan-Yu Chen, Kimberly Judith Dorans, Katherine Minjee Chung, Arjun Bhutkar, Erin Hong, Elisa M. Noll, Martin R. Sprick, Andreas Trumpp, Tyler Jacksanti-pPRAS40(T246) (CST 2997, 1:1000), rabbit anti-PTEN (CST 9559, 1:1000), rabbit anti-INPP4B (Abcam ab81269, 1:1000), rabbit anti-pS6(S235/236) (CST 4858, 1:2000), mouse anti-S6 (CST 2317, 1:1000), rabbit anti-4EBP1(S65)

(9) In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at EndosomesCancer discoveryJuly 1, 2015Li Chew C, Lunardi A, Gulluni F, Ruan DT, Chen M, Salmena L, Nishino M, Papa A, Ng C, Fung J, et al.

(10) PI3K pathway activation in high-grade ductal carcinoma in situ--implications for progression to invasive breast carcinomaClinical cancer research : an official journal of the American Association for Cancer ResearchMay 1, 2014Rita A Sakr, Britta Weigelt, Sarat Chandarlapaty, Victor P Andrade, Elena Guerini-Rocco, Dilip Giri, Charlotte K Y Ng, Catherine F Cowell, Neal Rosen, Jorge S Reis-Filho, Tari A King

(11) Alterations of INPP4B, PIK3CA and pAkt of the PI3K pathway are associated with squamous cell carcinoma of the lungCancer medicineApril 1, 2014Annika Stjernström, Christina Karlsson, Oswaldo J Fernandez, Peter Söderkvist, Mats G Karlsson, Lena K Thunell

(12) Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast CancerCancer DiscoveryNovember 1, 2012Ashish Juvekar et al.Phospho DNA-PK/PRKDC Ser2056 (3892-1) from Epitomics, Inc. CD31 (ab28364), Actin (ab6276), INPP4B (ab81269) from Abcam; pADPr (sc56198) from Santacruz Biotechnology; and Ki-67 (RM-9106) was purchased from Thermo Scientific

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Anti-INPP4B antibody [EPR3108Y] from Abcam

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Anti-INPP4B antibody [EPR3108Y] from Abcam

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