The Heat Shock Protein 27 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CMT2F, HSP1, HSP25, and HSPB1. This antibody recognizes Human antigen. The Heat Shock Protein 27 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
HSP27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. HSP27 synthesis is induced by elevated temperature as well as estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosphilia HSP?s and mammalian alpha-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore, HSP27 may be useful in classifying various hormone sensitive tumors