MyBioSource.com's Anti-LAMP1 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Anti-LAMP1 antibody was generated using CD107a, and LAMP1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Description: Rabbit IgG polyclonal antibody for Lysosome-associated membrane glycoprotein 1(LAMP1) detection. Tested with WB in Human, Mouse, Rat.
Background: LAMP1(lysosomal-associated membrane protein 1) also called LAMPA, LGP120 or CD107A, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells. By means of in situ hybridization, Mattei et al.(1990) assigned the LAMP1 gene to chromosome 13q34. A related gene, which may be a pseudogene, mapped to chromosome 12p13.3. Hybridization of LAMP1 cDNA to chromosome 12p13.3 was observed even when probes representing different portions of the LAMP1 cDNA were used