Fig 1: Effects of different theaflavin monomers on the mRNA and protein levels of MRP1, MRP2, MRP3, P-gp and BCRP in Caco-2 cells. (A) Effect of theaflavins on mRNA levels of efflux transporters. (B) Effect of theaflavins on protein levels of efflux transporters. Ctrl: Caco-2 cells were incubated with HBSS; TF, TF3G, TF3’G and TFDG: Caco-2 cells were incubated with TF, TF3G, TF3’G and TFDG. Results are expressed as means ± SD (N = 3). Different small letters indicate significant difference between different treatments at p<.05.