Description
Product Characteristics:
LZIC is a 190 amino acid protein that belongs to the CTNNBIP1 family. Ubiquitously expressed, LZIC is found at highest levels in kidney and is upregulated in a few gastric carcinomas. The gene encoding LZIC maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Subcellular location: Cytoplasm, Nucleus
Synonyms: Leucine zipper and CTNNBIP1 domain containing protein, Leucine zipper and ICAT homologous domain containing protein, leucine zipper domain and ICAT homologous domain containing, LZIC antibodyprotein LZIC, LZIC_HUMAN.
Target Information: Please see product details or send an inquiry to antibodies-online for additional target information