Description
Product Characteristics:
Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. SCCA2 may act as a protease inhibitor to modulate the host immune response against tumor cells.
Synonyms: HsT1196, Protein T4 A, Protein T4-A, SCC, SCCA PD, SCCA-1, SCCA1, SCCAPD, Serine or cysteine proteinase inhibitor clade B ovalbumin member 3, Serpin B3, Serpin peptidase inhibitor clade B ovalbumin member 3, SERPINB3, SPB3_HUMAN, Squamous cell carcinoma antigen 1, T4 A, T4A, SCCA 2, SCCA2, Leupin, Peptidase inhibitor 11, PI 11, PI-11, PI11, Protease inhibitor leucine serpin, SCCA-2, SCCA1, SCCA2/SCCA1 fusion protein, Serine or cysteine proteinase inhibitor, clade B ovalbumin, member 4, Serpin B4, Serpin peptidase inhibitor, clade B ovalbumin, member 4, SERPINB 4, SERPINB4, SPB4_HUMAN, Squamous cell carcinoma antigen 1, Squamous cell carcinoma antigen 2.
Target Information: May act as a protease inhibitor to modulate the host immune response against tumor cells