Description
Product Characteristics: 55kDa MW monocyte surface antigen identified by monoclonal antibodies belonging to the CD14 cluster and found on peripheral blood monocytes and weakly on granulocytes. Monocytic cells, interfollicular dendritic cells and dendritic reticulum cells are stained in sections of lymphoid tissue sections.
Target Information: The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]