Description
Product Characteristics:
Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.
Subcellular location: Cell membrane
Synonyms: T cell lymphoma invasion and metastasis 1, T lymphoma invasion and metastasis inducing TIAM1 protein, T-lymphoma invasion and metastasis-inducing protein 1, TIAM-1, TIAM1, TIAM1_HUMAN.
Target Information: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA