Description
Product Characteristics: Nbr1 acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets. Synonyms: Polyclonal Nbr1 antibody, Anti-Nbr1 antibody, neighbor of Brca1 gene 1 antibody, mKIAA0049 antibody.
Target Information: The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]