Description
Product Characteristics:
May play a role as a mediator of inflammation and angiogenesis.
Subcellular location: Extracellular matrix
Synonyms: B94, EXOC3L3, Tumor necrosis factor alpha-induced protein 2, TNF alpha-induced protein 2, Primary response gene B94 protein, TNFAIP2
Target Information: This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008]