Description
Product Characteristics: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Eras plays an important role in the tumor-like growth properties of embryonic stem cells. Synonyms: Polyclonal Eras antibody, Anti-Eras antibody, ES cell-expressed Ras antibody, HRAS2 antibody, HRasp antibody, Ha-Ras2 antibody, ecat5 antibody.
Target Information: This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]