Description
Product Characteristics:
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
Subcellular location: Cell membrane
Synonyms: NMDAR1 C1 (phospho S896), p-NMDAR1 C1 (phospho S896), NMDAR1(Phospho-Ser896), NMDAR1(Phospho-S896), NMDAR1 C1 (phospho S896), p-NMDAR1(S896), p-NMDAR1(Ser896), NMDA-NR1, N-Methyl-d-Asprtate receptor 1, GRIN1, NMDA1, NR1, Glutamate [NMDA] receptor subunit zeta 1, Glutamate receptor ionotropic N methyl D aspartate 1, Grin 1, Grin1, N methyl D aspartate receptor channel, N-methyl-D-aspartate receptor, N-methyl-D-aspartate receptor subunit NR1, NMD-R1, NMDA 1, NMDA NR1, NMDA R1, NMDA receptor 1, NMDA1, NMDAR 1, NMDAR, NR 1, NMDZ1_HUMAN.
Target Information: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]