Fig 1: High salt intake induced significant phosphorylation changes of Hsp27 and GAP43. Phosphorylation level of Hsp27(Ser15) (a) and GAP43(Ser41) (b) were validated by western blotting. Data are expressed as the mean±SD of three independent experiments (n = 8 in each group). *p < 0.001 vs. NS group or NC group. NS: sham operation + normal salt diet; NC: 5/6 Nx + normal salt diet; HC: 5/6 Nx + high salt diet; 5/6 Nx: 5/6 nephrectomy.