SPON1 Polyclonal Antibody bs-7520R from Bioss Inc.

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Molecular oncology
February 01 2023

Fig 1: Validation of TNXB and SPON1 expression. (A) Western blot analysis of TNXB and SPON1 expression in tumor tissues. (B) Statistical analysis of the results shown in A (n = 5). (C) Western blot analysis of TNXB and SPON1 expression in gastric cancer cells. (D) Statistical analysis of the results shown in C (n = 3). *P < 0.05; ** P < 0.01; ns, no significance. (E) Immunohistochemistry validation of TNXB and SPON1 expression in FFPE samples. Tumor samples from three individual patients in each group were examined. Magnification: 100×, scale bar: 200 μm. For B and D: error bars indicate SEM, unpaired two‐tailed Student's t‐test.
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Molecular oncology
February 01 2023

Fig 2: TNXB and SPON1 are potential biomarkers of lymph node metastasis in GAC. (A) Heatmap of top 50 most significantly changed proteins (smallest P value ranking) in primary tumors from GAC patients. (B) Protein–protein interaction network of top 30 upregulated proteins, including TNXB, SPON1, and their interaction proteins. (C) Expression of TNXB and SPON1 at mRNA level from The Cancer Genome Atlas (TCGA). Limma was used for differential gene expression analysis. (D) Correlation of protein expression between SPON1 and TNXB. Pearson's correlation was calculated. (E) Correlation of mRNA expression between SPON1 and TNXB from TCGA. Spearman's rank correlation was calculated. (F, G) Overall survival (F) and progression‐free interval (G) of GAC patients stratified by expression level of TNXB and SPON1 combined.

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SPON1 Polyclonal Antibody

The SPON1 Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to SPON1, and Spondin 1. This antibody recognizes Mouse, and Rat antigen. The SPON1 Polyclonal Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.

Description

Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell

Molecular oncology

Molecular oncology

SPON1 Polyclonal Antibody from Bioss Inc.

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Bioss Inc.

Citations (1)

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SPON1 Polyclonal Antibody from Bioss Inc.

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