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Antibodies
Anti-xCT antibody
Anti-xCT antibody from Abcam
Be the first to write a review!
Citations:
(97)
Supplier Page
Supplier Page from
Abcam for
Anti-xCT antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-xCT antibody
Company
Abcam
Price
Supplier Page
View Company Product Page
Catalog Number
ab37185
Antibody Type
Primary
Applications
Immunocytochemistry/ Immunofluorescence, Western blot
Isotype
IgG
Quantity
100 UL
Host
Rabbit
Clonality
Polyclonal
Conjugate/Tag
Unconjugated
Format
Affinity purified antibody
Concentration
1 mg/ml
Gene Name
SLC7A11
Reactivity
Human, Mouse
Target
xCT
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (97)
(1)
Circ_0000140 Alters miR-527/SLC7A11-Mediated Ferroptosis to Influence Oral Squamous Cell Carcinoma Cell Resistance to DDP
Pharmgenomics Pers Med
December 13, 2023
Yu Ma, Jinbo Gao, Hongning Guo
these blots were blocked with 5% skim milk before probing overnight with anti-SLC7A11 (
Abcam
, USA,
ab37185
) and anti-β-actin (
Abcam
,
ab8227
) at 4°C. After probing for 2 h using secondary antibodies at room temperature,
(2)
Gankyrin inhibits ferroptosis through the p53/SLC7A11/GPX4 axis in triple-negative breast cancer cells
Sci Rep
December 8, 2023
Ming Lei, Yun-Long Zhang, Feng-Ying Huang, Heng-Yu Chen, Ming-Hui Chen, Ri-Hong Wu, Shu-Zhen Dai, Gui-Sheng He, Guang-Hong Tan, Wu-Ping Zheng
DNK)53, a
mouse
monoclonal anti-MDM2 antibody (SMP14 Santa Cruz)12, a rabbit monoclonal Anti-SLC7A11 (
ab37185
Abcam
)56, and a rabbit monoclonal
Anti-Glutathione Peroxidase 4
(
ab125066
,
Abcam
)56. Finally, goat anti-rabbit
(3)
Identification and validation of a ferroptosis-related signature for prediction of the prognosis and tumor microenvironment in patients with chromophobe renal cell carcinoma
BMC Cancer
November 8, 2023
Shuai Liu, Yu Yao, Mingyu Hou, Jingchang Mei, Lijiang Sun, Guiming Zhang
Anti-Transferrin Receptor (TFRC) (dilution:
1:400
;
ab214039
,
Abcam
, Cambridge, UK) and
anti-xCT
(dilution:
1:600
;
ab37185
,
Abcam
, Cambridge, UK) antibodies were applied to for 90 min at 4 °C. The sections were then washed
(4)
Inhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLC
Cell Death & Disease
November 3, 2023
Linna Du, Han Yang, Yufei Ren, Yanli Ding, Yichao Xu, Xiaolin Zi, Hongmin Liu, Pengxing He
KM9001T),
ACSL4
(
Invitrogen
,
PA527137
),
TFRC
(
Abcam
,
ab214039
),
GPX4
(
Abcam
,
ab125066
), xCT (
Abcam
,
ab37185
),
ATF4
(
Cell Signaling Technology
,
11815
),
LSD1
(
Cell Signaling Technology
,
2184
), H3K9me2 (
Cell Signaling Technology
(5)
The gut metabolite 3-hydroxyphenylacetic acid rejuvenates spermatogenic dysfunction in aged mice through GPX4-mediated ferroptosis
Microbiome
September 27, 2023
Zirun Jin, Yuzhuo Yang, Yalei Cao, Qi Wen, Yu Xi, Jianxing Cheng, Qiancheng Zhao, Jiaming Weng, Kai Hong, Hui Jiang,
et al.
polyclonal to xCT (Cystine/glutamate transporter; Slc7a11, Solute carrier family 7 member 11,
1:1000
,
ab37185
,
Abcam
),
mouse
monoclonal to α-tubulin (
1:3000
,
3873S
,
Cell Signaling Technology
), and
mouse
monoclonal
(6)
Chronic exposure to inorganic arsenic and fluoride induces redox imbalance, inhibits the transsulfuration pathway, and alters glutamate receptor expression in the brain, resulting in memory impairment in adult male mouse offspring
Archives of Toxicology
July 23, 2023
Wendy L. González-Alfonso, Petrosyan Pavel, Hernández-Mercado Karina, Luz M. Del Razo, Luz C. Sanchez-Peña, Angélica Zepeda, María E. Gonsebatt
obtained from EM Science (Gibbstown, NJ, USA). For
Western blots
, primary rabbit antibodies against xCT (
ab37185
),
EAAT3
(
ab124802
), GLAST (
ab416
), GLT1 (
ab41621
), NR2B (
ab65783
),
GluA2
(
ab133477
), Synaptophysin (SY38,
(7)
Mechanism of Cell Death by Combined Treatment with an xCT Inhibitor and Paclitaxel: An Alternative Therapeutic Strategy for Patients with Ovarian Clear Cell Carcinoma
International journal of molecular sciences
July 22, 2023
Idei U, Ohta T, Yamatani H, Seino M, Nagase S.
CO2. 4.2. Antibodies and Reagents The following antibodies were purchased against: xCT (
1:1000
; cat. no.
ab37185
;
Abcam
; Cambridge, UK), cleaved-
PARP
(
1:1000
; cat. no.
9541
;
Cell Signaling Technology
; Danvers, MA,
(8)
Inositol polyphosphate multikinase modulates redox signaling through nuclear factor erythroid 2-related factor 2 and glutathione metabolism
iScience
July 21, 2023
Tyagi R, Chakraborty S, Tripathi SJ, Jung IR, Kim SF, Snyder SH, Paul BD.
RRID:AB_2137173" Anti-Nrf2 (
1:100
),
Cell Signaling
,"Cat#
12721
, RRID:AB_2715528"
Anti-xCT (SLC7A11
) (
1:1000
),
Abcam
,"Cat#
ab37185
, RRID:AB_778944" ,, "Chemicals, peptides, and recombinant proteins","Chemicals, peptides, and recombinant
(9)
Upregulation of CDGSH iron sulfur domain 2 attenuates cerebral ischemia/reperfusion injury
Neural regeneration research
July 1, 2023
Hu M, Huang J, Chen L, Sun XR, Yao ZM, Tong XH, Jin WJ, Zhang YX, Dong SY.
CST
, Boston, MA, USA, Cat#
60758
, RRID: AB_943513), xCT (rabbit,
1:2000
, Abcam, Cambridge, UK, Cat#
ab37185
, RRID: AB_778944),
GPX4
(rabbit,
1:2000
, Cat#
ab125066
, RRID: AB_10973901,
Abcam
), transferrin receptor1
(10)
Protein Kinase B (PKB/AKT) Protects IDH-Mutated Glioma from Ferroptosis via Nrf2
Clinical Cancer Research
April 3, 2023
Yang Liu, Fu-Ju Chou, Fengchao Lang, Meili Zhang, Hua Song, Wei Zhang, Dionne L. Davis, Nicole J. Briceno, Yang Zhang, Patrick J. Cimino,
et al.
3063
,
1:1000
), phosphor-GSK3β (Ser9,
CST
,
5558
,
1:1000
) , GSK3β (
CST
,
12456
,
1:1,000
), xCT (
Abcam
,
ab37185
,
1:1,000
), NQO1 (
Abcam
,
ab34173
,
1:1,000
), GCLC (
Abcam
,
ab41463
,
1:1,000
), HA-tag (
CST
,
3724
,
1:1,000
),
(11)
B cell-derived anti-beta 2 glycoprotein I antibody mediates hyperhomocysteinemia-aggravated hypertensive glomerular lesions by triggering ferroptosis
Signal transduction and targeted therapy
March 13, 2023
Du X, Ma X, Tan Y, Shao F, Li C, Zhao Y, Miao Y, Han L, Dang G, Song Y,
et al
.
USA).
Anti-xCT
(catalytic subunit of cystine/glutamate antiporter System Xc-, also called
SLC7A11
,
ab37185
), anti-LOX15 (Lipoxygenase 15,
ab23691
), anti-GPX4 (glutathione peroxidase 4,
ab125066
), and anti-TFR
(12)
Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation
Cell Death & Differentiation
February 1, 2023
Fabienne Müller, Jonathan K. M. Lim, Christina M. Bebber, Eric Seidel, Sofya Tishina, Alina Dahlhaus, Jenny Stroh, Julia Beck, Fatma Isil Yapici, Keiko Nakayama,
et al.
(Sigma). Antibodies Ras (
clone
RAS10, #
05-516
;
Millipore
,
1:1000
), GPX4 (
Abcam
,
ab41787
,
1:2,000
), xCT (
Abcam
,
ab37185
,
1:2000
), ß-Actin (
Sigma
,
A1978
,
1:10,000
),
GAPDH
(
Cell Signaling
, #
97166
,
1:2000
), FSP1 (previously
(13)
Erk1/2-Dependent HNSCC Cell Susceptibility to Erastin-Induced Ferroptosis
Cells
January 16, 2023
Dragana Savic, Teresa Bernadette Steinbichler, Julia Ingruber, Giulia Negro, Bertram Aschenbrenner, Herbert Riechelmann, Ute Ganswindt, Sergej Skvortsov, József Dudás, Ira-Ida Skvortsova
Acquisition Enzyme
immunohistochemistry (IHC
) for
xCT
was carried out using the
mouse
monoclonal
anti-xCT
antibody (
ab37185
;
Abcam
, Cambridge, UK), and the reaction was developed using a universal secondary antibody (Roche Ventana,
(14)
Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis
Frontiers in pharmacology
January 1, 2023
Liu X, Peng X, Cen S, Yang C, Ma Z, Shi X.
were used:
Nrf2
at
1:1,000
dilution (
ab137550
,
Abcam
, United Kingdom),
SLC7A11
at
1:1,000
dilution (
ab37185
,
Abcam
, United Kingdom),
GPX4
at
1:1,000
dilution (
ab125066
,
Abcam
, United Kingdom),
HO-1
and β-Actin
(15)
Integrated analysis of FKBP1A/SLC3A2 axis in everolimus inducing ferroptosis of breast cancer and anti-proliferation of T lymphocyte
International journal of medical sciences
January 1, 2023
Chen Z, Li R, Fang M, Wang Y, Bi A, Yang L, Song T, Li Y, Li Q, Lin B,
et al
.
dilutions:
SLC3A2
(
1:1000
,
Affinity
, #
DF7468
),
FKBP1A
(
1:1000
,
Proteintech
, #
10273-1-AP
), SLC7A11 (
Abcam
,
ab37185
),
GPX4
(
Abcam
,
ab125066
),
IL-9R
(
Santa Cruz
,
sc-515622
),
GAPDH
(
1:1000
,
Proteintech
, #
60004-1-Ig
), HA
(16)
High co‐expression of SLC7A11 and GPX4 as a predictor of platinum resistance and poor prognosis in patients with epithelial ovarian cancer
BJOG: An International Journal of Obstetrics & Gynaecology
December 9, 2022
Xiaodong Wu, Shizhen Shen, Jiale Qin, Weidong Fei, Fengyun Fan, Jiaxin Gu, Tao Shen, Tao Zhang, Xiaodong Cheng
peroxides. The sections were then incubated with anti‐SLC7A11 (
1:600
in NCM universal antibody diluent,
ab37185
;
Abcam
) and anti‐
GPX4
antibodies (
1:300
in NCM universal antibody diluent,
ab125066
;
Abcam
). Two serial
(17)
AGuIX nanoparticles enhance ionizing radiation-induced ferroptosis on tumor cells by targeting the NRF2-GPX4 signaling pathway
Journal of nanobiotechnology
October 14, 2022
Sun H, Cai H, Xu C, Zhai H, Lux F, Xie Y, Feng L, Du L, Liu Y, Sun X,
et al
.
(
CST
, #
4588
),
KU80
(
CST
, #
2753
),
GPX4
(
Abcam
,
ab125066
),
ACSL4
(
Abcam
,
ab155282
), SLC7A11/xCT (
Abcam
,
ab37185
), TFR (
Abcam
,
ab84036
), and FTH1 (
Abcam
,
ab65080
). A digital imaging system (Bio-Rad, Hercules, CA,
(18)
Regulating Nrf2-GPx4 axis by bicyclol can prevent ferroptosis in carbon tetrachloride-induced acute liver injury in mice
Cell Death Discovery
September 7, 2022
Tianming Zhao, Zihan Yu, Lei Zhou, Xiaoyu Wang, Yangyang Hui, Lihong Mao, Xiaofei Fan, Bangmao Wang, Xingliang Zhao, Chao Sun
-
polyacrylamide gel electrophoresis
and subsequently transferred to nitrocellulose
membranes
. Primary antibodies used were
anti-xCT
(
ab37185
,
Abcam
,
1:1000
), anti-
GPx4
(
ab125066
,
Abcam
,
1:1000
), anti-
ACSL4
(
DF12141
,
Affinity
,
1:1000
), anti-
p53
(19)
The establishment of polypeptide PSMA‐targeted chimeric antigen receptor‐engineered natural killer cells for castration‐resistant prostate cancer and the induction of ferroptosis‐related cell death
Cancer Communications
August 1, 2022
Liyuan Wu et al.
(SLC3A2) antibody (
1:2500
;
ab244356
) and anti‐solute carrier family 7‐member 11 (SLC7A11) antibody (
1:500
;
ab37185
) were purchased from
Abcam
. The
PSMA
,
CD56
,
SLC3A2
, and SLC7A11 protein expression levels were assessed
(20)
SIRT6 promotes ferroptosis and attenuates glycolysis in pancreatic cancer through regulation of the NF‑κB pathway
Experimental and Therapeutic Medicine
June 8, 2022
Shuangxi Gong, Lixin Xiong, Zhen Luo, Qinghua Yin, Ming Huang, Yang Zhou, Jian Li
(
1:1,000
; catalog no.
ab76429
),
GPX4
(
1:1,000
; catalog no.
ab125066
), SLC7A11 (
1:1,000
; catalog no.
ab37185
),
HK2
(
1:1,000
; catalog no.
ab104836
) and lactate dehydrogenase A (LDHA;
1:1,000
; catalog no.
ab134187
)
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Anti-xCT antibody from Abcam
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