Fig 1: The expression of P-gp in A549/ADR was apparently suppressed by the combined administration of 5FU and UBE. UBE treatment suppressed the expression of PIM-3 while 5FU treatment down-regulated the expression of p-PI3K and p-AKT (*P < .05 compared with UNTREATED group; **P < .05 compared with 5FU group). A, The expression of P-gp mRNA was substantially attenuated in A549/ADR cells by the combined administration of 5FU and UBE. B, The expression of P-gp protein was substantially attenuated in A549/ADR cells by the combined administration of 5FU and UBE. C, UBE treatment suppressed the expression of PIM-3 while 5FU treatment down-regulated the expression of p-PI3K and p-AKT
Supplier Page from Abcam for Anti-PI 3 Kinase p85 alpha antibody [6G10]