Fig 1: Effect of acute cold stress on glucose metabolism in the liver. (A) Protein kinase B (AKT) protein levels and phosphorylation state in the liver; (B) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2) protein levels and phosphorylation state in the liver; (C) glycogen synthase kinase-3ß (GSK3ß) protein levels and phosphorylation state in the liver; (D) 160 kDa AKT substrate (AS160) protein levels and phosphorylation state in the liver. The data are presented as mean ± SEM (n = 8). Statistically significant differences are indicated, * p < 0.05 and ** p < 0.01.