Fig 1: SAG transgenic expression altered multiple signal pathways. (A) Western blot analysis of the indicated proteins in lysates of pancreatic tissues from two independent 6-month-old KC and KCS mice. (B) Immunohistochemical assessment of c-Jun, Erbin, p-S6K, p-4EBP1, and p-mTOR in KC and KCS pancreata at 6 months of age. Scale bar, 100 μm.