Fig 2: The correlations between PSTPIP1/PILRA and immune biomarkers in LUAD. Scatter plots showing the correlation between (A) PSTPIP1 and PD-L1, (B) PSTPIP1 and IFN-?, (C) PILRA and PD-L1, and (D) PILRA and IFN-? in the LUAD samples (n = 515). Violin plots showing the expression of (E) PSTPIP1 and (F) PILRA in the LUAD samples with different degrees of differentiation (including 167 with poor differentiation, 209 with moderate differentiation, and 60 with well differentiation). ns indicates p = 0.05, *p < 0.05.

Fig 3: Histopathological examples of PSTPIP1/PILRA expression and tumor-infiltrating lymphocytes (TILs) in LUAD. (A) PSTPIP1 and PILRA expression is demonstrated by brown staining, and the bar plot shows the average optical density of PSTPIP1 and PILRA in the PD-L1–positive or PD-L1–negative LUAD tissue samples. (B) The TILs are displayed as purple spots in hematoxylin and eosin staining, and bar plots show the stromal TILs in tissue samples with high and low PSTPIP1/PILRA expressions. *p < 0.05.