Brilliant Violet 421(TM) anti-mouse IL-17A 506925 from BioLegend

Product Specs
ItemBrilliant Violet 421(TM) anti-mouse IL-17A
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number506925
ReactivityMouse
Quantity125 µL
NCBI Gene AliasesCtla-8, Ctla8, IL-17, IL-17A, Il17
IsotypeIgG1, Kappa
HostRat
ApplicationsIntracellular Staining for Flow Cytometry (ICFC)
CloneTC11-18H10.1
Conjugate/TagBrilliant Violet 421™
Antibody TypePrimary
NCBI Full Gene Nameinterleukin 17A
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
ImmunogenE. coli expressed, recombinant mouse IL-17A
ClonalityMonoclonal
TargetIL-17A

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
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Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) CCL5 promotes LFA-1 expression in Th17 cells and induces LCK and ZAP70 activation in a mouse model of Parkinson’s diseaseFrontiers in Aging NeuroscienceNovember 3, 2023Jingwei Zhao, Ke An, Zhijuan Mao, Yi Qu, Danlei Wang, Jiangting Li, Zhe Min, Zheng Xueanother 45 min. A BV421-labeled antibody targeting the Th17-specific marker IL-17A (5 μg/mL, BioLegend, 506925) was used to perform pZAP70 or pLCK staining. After incubation, the cell suspension was centrifuged,

(2) Tuberous Sclerosis Complex 1 Deficiency in Macrophages Promotes Unclassical Inflammatory Response to Lipopolysaccharide In Vitro and Dextran Sodium Sulfate-Induced Colitis in MiceAging and diseaseDecember 1, 2022Huawen Xu, Yang Zhao, Qingjie Zhao, Mingpu Shi, Zhaoqi Zhang, Wenjun Ding, Yong Zhaoanti-mF4/80-PE (Cat#: 123110; BioLegend), anti-mIL-17A-PE (Cat#: 506904; BioLegend), anti-mIL-17A-BV421 (Cat#: 506925; BioLegend), anti-mIFN-γ-PE(Cat#: 505808; BioLegend), anti-mIFN-γ-FITC (Cat#: 505806; BioLegend), anti-m

(3) A minimally-edited mouse model for infection with multiple SARS-CoV-2 strainsFrontiers in ImmunologyNovember 14, 2022Sandra Nakandakari-Higa, Roham Parsa, Bernardo S. Reis, Renan V. H. de Carvalho, Luka Mesin, Hans-Heinrich Hoffmann, Juliana Bortolatto, Hiromi Muramatsu, Paulo. J. C. Lin, Angelina M. Bilate, et al.(BD Biosciences Cat. No. 560660), TNF-α-PE-Cy7 (BioLegend Cat. No. 506323), IL-17α-BV421 (BioLegend Cat. No. 506925), B220-BV785 (BioLegend Cat. No. 103245), FAS-PE-Cy7 (BioLegend Cat. No. 152617), CD38- PerCP-Cy5.5

(4) NOD2 Signaling Circuitry during Allergen Sensitization Does Not Worsen Experimental Neutrophilic Asthma but Promotes a Th2/Th17 Profile in Asthma Patients but Not Healthy SubjectsInternational Journal of Molecular SciencesOctober 6, 2022MÃ©lodie BoutÃ©, Saliha Ait Yahia, Ying Fan, Daniel Alvarez-Simon, Han Vorng, Joanne Balsamelli, Julie Nanou, Patricia de Nadai, CÃ©cile Chenivesse, Anne TsicopoulosBrilliant Violet 605,100547,Biolegend,0.25 CD45 APC Cy7,557659,BD,0.3 IL-17A Brilliant Violet 421,506925,Biolegend,0.25 Antibodies used for flow cytometry assays.

(5) Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine modelsJCI insightJanuary 25, 2022Palathingal Bava E, George J, Tarique M, Iyer S, Sahay P, Gomez Aguilar B, Edwards DB, Giri B, Sethi V, Jain T, et al.

(6) A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidateNatureFebruary 1, 2021Sanchez-Felipe L, Vercruysse T, Sharma S, Ma J, Lemmens V, Van Looveren D, Arkalagud Javarappa MP, Boudewijns R, Malengier-Devlies B, Liesenborghs L, et al.

(7) The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24ImmunityAugust 18, 2020Chong WP, Mattapallil MJ, Raychaudhuri K, Bing SJ, Wu S, Zhong Y, Wang W, Chen Z, Silver PB, Jittayasothorn Y, et al.

(8) STING couples with PI3K to regulate actin reorganization during BCR activationScience advancesApril 1, 2020Jing Y, Dai X, Yang L, Kang D, Jiang P, Li N, Cheng J, Li J, Miller H, Ren B, et al.(BioLegend, 504106), PE/CY7-anti-IFN-γ (BioLegend, 505826), and Brilliant Violet 421-anti-IL-17A (BioLegend, 506925). For Tfh cell analysis, splenic lymphocytes were prestained with CXCR5 (551961, BD Biosciences) at

(9) Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapyThe Journal of clinical investigationJanuary 2, 2020Sharma NS, Gupta VK, Garrido VT, Hadad R, Durden BC, Kesh K, Giri B, Ferrantella A, Dudeja V, Saluja A, et al.

(10) NLRP3 Inflammasome Regulates Development of Systemic Inflammatory Response and Compensatory Anti-Inflammatory Response Syndromes in Mice With Acute PancreatitisGastroenterologyJanuary 1, 2020Sendler M, van den Brandt C, Glaubitz J, Wilden A, Golchert J, Weiss FU, Homuth G, De Freitas Chama LL, Mishra N, Mahajan UM, et al.

(11) Effector T_H17 Cells Give Rise to Long-Lived T_RM Cells that Are Essential for an Immediate Response against Bacterial InfectionCellAugust 22, 2019Amezcua Vesely MC, Pallis P, Bielecki P, Low JS, Zhao J, Harman CCD, Kroehling L, Jackson R, Bailis W, Licona-Limón P, et al.Alexa 700 clone 104,Biolegend,109822 Rat IgG1 anti-mouse IL17a Pacific blue TC11-18H10.1,Biolegend,506925 Rat IgG1 anti mouse IFNg APC clone XMG1.2,BD PHARMIGEN,554413 Rat IgG2a anti-mouse CD122 clone 5H4,Biolegend,105905 Purified

(12) Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3Molecular cellApril 4, 2019Ning X, Wang Y, Jing M, Sha M, Lv M, Gao P, Zhang R, Huang X, Feng JM, Jiang Z.

(13) PRMT5 Associates With the FOXP3 Homomer and When Disabled Enhances Targeted p185^erbB2/neu Tumor ImmunotherapyFrontiers in immunologyJanuary 1, 2019Nagai Y, Ji MQ, Zhu F, Xiao Y, Tanaka Y, Kambayashi T, Fujimoto S, Goldberg MM, Zhang H, Li B, et al.

(14) Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapyOncoimmunologyJanuary 1, 2019Findlay EG, Currie AJ, Zhang A, Ovciarikova J, Young L, Stevens H, McHugh BJ, Canel M, Gray M, Milling SWF, et al.103016); CD44 (IM7, Biolegend, 103039); PD1 (29F.1A12, Biolegend, 135016); IL17A (TC11-18H10.1, Biolegend, 506925); IFN-γ (XMG1.2, Biolegend, 505825); TNF (Mab11, Biolegend, 506313); TNF (MP6-XT26, Ebioscience, 48–7321-82);

(15) Critical Role for the Microbiota in CX₃CR1⁺ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell ResponsesImmunityJuly 17, 2018Kim M, Galan C, Hill AA, Wu WJ, Fehlner-Peach H, Song HW, Schady D, Bettini ML, Simpson KW, Longman RS, et al.

(16) Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune ArthritisImmunityJune 19, 2018Hirota K, Hashimoto M, Ito Y, Matsuura M, Ito H, Tanaka M, Watanabe H, Kondoh G, Tanaka A, Yasuda K, et al.

(17) Regulatory T cells are required for normal and activin-promoted wound repair in miceEuropean journal of immunologyJune 1, 2018Haertel E, Joshi N, Hiebert P, Kopf M, Werner S.

(18) Innate lymphoid cells contribute to allergic airway disease exacerbation by obesityThe Journal of allergy and clinical immunologyNovember 1, 2016Everaere L, Ait-Yahia S, Molendi-Coste O, Vorng H, Quemener S, LeVu P, Fleury S, Bouchaert E, Fan Y, Duez C, et al.

(19) Alterations in antigen-specific naive CD4 T cell precursors after sepsis impairs their responsiveness to pathogen challengeJournal of immunology (Baltimore, Md. : 1950)February 15, 2015Cabrera-Perez J, Condotta SA, James BR, Kashem SW, Brincks EL, Rai D, Kucaba TA, Badovinac VP, Griffith TS.

(20) Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced ArthritisPloS oneJanuary 1, 2015Alves CH, Ober-Blöbaum JL, Brouwers-Haspels I, Asmawidjaja PS, Mus AM, Razawy W, Molendijk M, Clausen BE, Lubberts E.

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Frontiers in Aging Neuroscience

Brilliant Violet 421(TM) anti-mouse IL-17A from BioLegend

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Brilliant Violet 421(TM) anti-mouse IL-17A from BioLegend

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