Phospho-GAP-43 (S41) Antibody PPS006 from R&D Systems, a Bio-Techne Brand | Biocompare.com

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Molecular metabolism
November 01 2022

Fig 1: GAP43 expression is downregulated in CGRP-positive neurons upon loss of adipose mTORC2. (A) Immunoblot analysis of inguinal WAT (iWAT) tissue from control and iAdRiKO mice two weeks after tamoxifen treatment. (n = 6; 6). (B) Immunoblot analysis of iWAT tissue from control and iAdRiKO mice four weeks after tamoxifen treatment. (n = 6; 6). (C) Immunoblot analysis of surgically denervated iWAT depot (denervation) compared to iWAT depot from sham-operated mice (sham). Neurofilament heavy polypeptide (NFH). (n = 5; 5). (D) Representative image of a large nerve bundle in iWAT of control mice immunostained with growth-associated protein 43 (GAP43)-pS41 and calcitonin gene-related peptide (CGRP). (N = 11; 9). (E) Representative image of a large nerve bundle in iWAT of control mice immunostained with GAP43-pS41 and tyrosine hydroxylase (TH). (N = 19; 11).

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R&D Systems, a Bio-Techne Brand for
Phospho-GAP-43 (S41) Antibody

The Phospho-GAP-43 (S41) Antibody from R&D Systems, a Bio-Techne Brand is a Rabbit Polyclonal antibody to GAP43, and Growth Associated Protein 43. This antibody recognizes Homo Sapiens, Human, Mouse, Rat, Bovine, Canine, Chicken/Bird, Non-Human Primate, Xenopus/Amphibian, and Zebrafish/Fish antigen. The Phospho-GAP-43 (S41) Antibody has been validated for the following applications: Western Blot.

Product Specs
ItemPhospho-GAP-43 (S41) Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberPPS006
NCBI Gene AliasesB-50, GAP-43, PP46
ApplicationsWestern Blot
Format100 µL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA and 50% glycerol
TargetGAP-43
Conjugate/TagUnconjugated
Quantity100 uL
HostRabbit
ReactivityHuman, Mouse, Rat, Bovine, Canine, Chicken, Primate, Xenopus, Zebrafish
IsotypeIgG
NCBI Full Gene Namegrowth associated protein 43
ClonalityPolyclonal
Modificationsp ser41
ImmunogenPhosphopeptide corresponding to amino acid residues surrounding the phospho-S41 of GAP-43
Brand/TrademarkR&D Systems, a Bio-Techne Brand
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageFor long-term storage, <= -20° C is recommended. Product is stable at <= -20° C for at least 1 year

Specifications/Features

Available conjugates: Unconjugated

Specificity: Specific for the ~50 kDa GAP-43 protein phosphorylated at S41 in Western blots. In some tissues the antibody also recognizes a higher molecular weight protein, that is also recognized by the Pan GAP-43 antibody. This may be a GAP-43 aggregate or oligomer

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

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