Description
Product Characteristics: NFATC2, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2, KIAA0611, NFAT1, NFATP, NFAT pre-existing subunit, NFAT transcription complex, preexisting component, OTTHUMP00000031291, T cell transcription factor NFAT1, nuclear factor of activated T-cells, cytoplasmic 2, nuclear factor of activated T-cells, preexisting component, preexisting nuclear factor of activated T-cells 2
Target Information: This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]