Description
Product Characteristics: CXCL13, chemokine (C-X-C motif) ligand 13, ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13, B-cell chemoattractant, B-cell-attracting chemokine 1, B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1), B-lymphocyte chemoattractant, chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant), small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant)
Target Information: B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq, Jul 2008]