Description
Product Characteristics: FUNCTION: Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception. SUBCELLULAR LOCATION: Cell membrane, Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons.,G Protein Signaling,Nuclear receptor MrgA10 RF-amide G protein-coupled receptor, Mrga10, MrgA, Mrgpra, MGC108580
Target Information: This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009]