Description
Product Characteristics: SWAP70, SWAP-70 protein, SWAP-70, KIAA0640, KIAA0640 protein, FLJ39540, HSPC321, SWAP switching B-cell complex 70 kDa subunit
Target Information: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity)