Description
Product Characteristics: PCSK6, proprotein convertase subtilisin/kexin type 6, PACE4, SPC4, paired basic amino acid cleaving system 4, subtilisin-like proprotein convertase 4, subtilisin-like protease, subtilisin/kexin-like protease PACE4
Target Information: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]