Fig 1: Klotho affected insulin sensitivity. (a). RT-qPCR of klotho levels. (b) CCK-8 detection was used to detect cell viability. (c) The cells were subjected to a glucose uptake assay. (d) Western blot of GLUT4, INSR-a, INSR-ß, IRS1, and IRS2 protein levels. *p < 0.05 compared with the NC group. #p < 0.05 compared with the HG group.
Fig 2: HG could induce IR in HTR-8/SVneo cells. GLUT4, INSR-a, INSR-ß, IRS1, and IRS2 protein levels were profiled by western blot. *p < 0.05 compared with the NC group.
Supplier Page from Abcam for Anti-Insulin Receptor alpha antibody