Anti-CDKN2A/p19ARF antibody ab80 from Abcam

Product Specs
ItemAnti-CDKN2A/p19ARF antibody
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab80
Antibody TypePrimary
ClonalityPolyclonal
HostRabbit
Quantity100 UG
ApplicationsELISA, Immunocytochemistry, Western blot
IsotypeIgG
Conjugate/TagUnconjugated
FormatThe serum has been purified on a peptide-NHS-activated Sepharose column. Specific antibodies have been eluted with 100 mM glycine pH 2.5. The purified antibodies have been dialysed against PBS pH 7.4
Concentration1 mg/ml
Research AreaEpigenetics
Gene NameCDKN2A
ReactivityMouse
TargetCDKN2A/p19ARF

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) IFNγ Transcribed by IRF1 in CD4+ Effector Memory T Cells Promotes Senescence-Associated Pulmonary FibrosisAging and diseaseDecember 1, 2023Chen H, Wang Q, Li J, Li Y, Chen A, Zhou J, Zhao J, Mao Z, Zhou Z, Zhang J, et al.experiments. Western blots Western blots were generated as previously described. Primary antibodies against p19 (ab80, Abcam, USA), p21 (sc-471, Santa Cruz Biotechnology Inc., USA), p16 (ab211542, Abcam, USA), p53 (sc-126,

(2) De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expressionbioRxivJuly 20, 2023Naveen Kumar Tangudu, Raquel Buj, Jiefei Wang, Aidan R. Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Maureen A. Lyons, Uma R. Chandran, Katherine M. AirdRabbit anti-p16 INK4A (Cell Signaling Technology, 29271; 1:1000); Rabbit anti-CDKN2A/p19 ARF (Abcam, ab80; 1:1000); mouse anti-β-actin (Sigma Aldrich, A1978; 1:10000). Secondary antibodies: Anti-mouse IgG, HRP-linked

(3) ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumorsNature communicationsMarch 3, 2023Mainwaring OJ, Weishaupt H, Zhao M, Rosén G, Borgenvik A, Breinschmid L, Verbaan AD, Richardson S, Thompson D, Clifford SC, et al.Cleaved Caspase-3 [Asp175] (Abcam, Cat # ab49899 (WB 1:500, IHC 1:1500)), CDKN2A/p19ARF (Abcam, Cat # ab80 (1:1000)), cMYC [Y69] (Abcam, Cat # ab32072 (WB 1:1000, IHC 1:500)), Cyclophilin B (Cell Signalling

(4) Ezh2 Inhibits Replicative Senescence of Atrial Fibroblasts Through Promotion of H3K27me3 in the Promoter Regions of CDKN2a and Timp4 GenesJournal of Inflammation ResearchAugust 16, 2022Yingze Li, Guojian Fang, Wei Cao, Jiali Yuan, Shuai Song, Hong Peng, Yuepeng Wang, Qunshan Wang(Abcam, ab137332), MMP8 (Abcam, ab53017), MMP13 (Abcam, ab39012), p16 (Abcam, ab211542), p19 (Abcam, ab80), p21 (Abcam, ab188224), collagen-I (Abcam, ab254113), collagen-III (Servicebio, GB111323), or GAPDH

(5) Helicobacter pylori pathogen inhibits cellular responses to oncogenic stress and apoptosisPLoS pathogensJune 1, 2022Palrasu M, Zaika E, Paulrasu K, Caspa Gokulan R, Suarez G, Que J, El-Rifai W, Peek RM Jr, Garcia-Buitrago M, Zaika AI.normal mouse IgG (sc-2025) from Santa Cruz Biotechnology (Santa Cruz, CA); p14ARF (ab185620) and p19ARF (ab80) from Abcam (Cambridge, MA); ULF/TRIP12 (A301-814A) and MKRN1 (A300-990A) from Bethyl Laboratories (Montgomery,

(6) N-Chlorotaurine Reduces the Lung and Systemic Inflammation in LPS-Induced Pneumonia in High Fat Diet-Induced Obese MiceMetabolitesApril 14, 2022Khanh Hoang N, Maegawa E, Murakami S, Schaffer SW, Ito T.Germany). For detection of Laminin, the frozen section was immunostained by using anti-laminin antibody (ab80, Abcam, Cambridge, UK; 1:100) and Alexa Fluor 488-conjugated second antibody (Life Technologies; 1:400)

(7) A murine mesenchymal stem cell model for initiating events in osteosarcomagenesis points to CDK4/CDK6 inhibition as a therapeutic targetLaboratory InvestigationApril 1, 2022Natasja Franceschini, Raffaele Gaeta, Paul Krimpenfort, Inge Briaire-de Bruijn, Alwine B. Kruisselbrink, Karoly Szuhai, Ieva PalubeckaitÄ—, Anne-Marie Cleton-Jansen, Judith V. M. G. BovÃ©eUK), p16 (1:1000, clone JC8, Immunologic, WellMed BV, Duiven, The Netherlands), p19 (1:5000, clone ab80, Abcam), Rb (1:500, clone G3-245, BD Pharmingen, San Diego, CA, USA), Histon H3 (1:1000, Cell Signalling,

(8) A Series of BRAF- and NRAS-Driven Murine Melanoma Cell Lines with Inducible Gene Modulation CapabilitiesJID InnovMarch 1, 2022Bok I, Angarita A, Douglass SM, Weeraratna AT, Karreth FA.United Kingdom), p16INK4a (1:2,000, catalog number ab211542; Abcam), p19ARF (1:1,000, catalog number ab80; Abcam), p53 (1:1,000, catalog number 3036-100; BioVision, Milpitas, CA), phosphorylated AKT S473 (1:2,000,

(9) Age-related GSK3β overexpression drives podocyte senescence and glomerular agingJournal of Clinical InvestigationFebruary 15, 2022Yudong Fang, Bohan Chen, Zhangsuo Liu, Athena Y. Gong, William T. Gunning, Yan Ge, Deepak Malhotra, Amira F. Gohara, Lance D. Dworkin, Rujun Gonganti-fibronectin (sc-9068, Santa Cruz Biotechnology); rabbit anti-fibronectin (ab2413, Abcam); rabbit anti-p19 (ab80, Abcam); rabbit anti-CDK2 (ab32147, Abcam); rabbit anti-CDK4 (ab199728, Abcam); rabbit anti–phosphorylated

(10) Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeriaAging (Albany NY)January 15, 2022Christina Manakanatas, Santhosh Kumar Ghadge, Azra Agic, Fatih Sarigol, Petra Fichtinger, Irmgard Fischer, Roland Foisner, Selma Osmanagic-MyersTween for 1 h at RT and stained with the following primary antibodies: rabbit anti-CDKN2A/p19ARF 1:100 (ab80, Abcam), rabbit anti-PECAM-1/CD31 1:30 (LB-B4737, LifeSpan BioScience) and rat anti-CD3 1:400 (MCA1477,

(11) p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced SkinOxidative medicine and cellular longevityJanuary 1, 2022Liang Y, Gu T, Peng S, Lin Y, Liu J, Wang X, Huang X, Zhang X, Zhu J, Zhao L, et al.30 μg protein was used for analysis. Primary antibodies against p16 (ab211542), p16 (ab152099), p19 (ab80), tumor necrosis factor-α (TNF-α) (ab183218), IL-1β (ab9722), NLRP3 (ab263899), ApoE (ab183597), NLRC4

(12) Stabilization of p18 by deubiquitylase CYLD is pivotal for cell cycle progression and viral replicationnpj Precision OncologyDecember 1, 2021Yueshuo Li et al.USA). Primary antibodies include anti-p18 INK4C (1:1000, Cat: ab192239), and anti-p19 (1:1000, Cat: ab80), p15 (1:1000, Cat: ab53034), p16 (1:1000, Cat: EPR20418), p21 (1:1000, Cat: ab109520), p27 (1:1000,

(13) Intramuscular injection of Botox causes tendon atrophy by induction of senescence of tendon-derived stem cellsStem Cell Research & TherapyDecember 1, 2021Peilin Chen et al.primary antibodies used for Western Blotting were purchased from either Abcam® (anti-CDKN2A/p19ARF ab80, anti-p16 ARC ab51243, anti-Tenomodulin ab2023276 and anti-MMP13 ab39012, anti-MMP9 ab38898, anti-beta

(14) Polycomb repressive complex 2 in adult hair follicle stem cells is dispensable for hair regenerationPLoS geneticsDecember 1, 2021Flora P, Li MY, Galbo PM Jr, Astorkia M, Zheng D, Ezhkova E.Cat#649601), Rabbit anti-LEF1 (1:100, Cell Signaling, Cat# 2230S), Rabbit anti-P19 (ARF) (1:200, Abcam, Cat#ab80), Goat anti-EDAR (1:100, R&D Systems, Cat# AF745) and Sheep anti-FOXC2 (1:100, R&D Systems, Cat# AF6989).

(15) Differential H4K16ac levels ensure a balance between quiescence and activation in hematopoietic stem cellsScience advancesAugust 1, 2021Pessoa Rodrigues C, Akhtar A.#A2066), H3 (1:5000; Active Motif, #39763), p16INKA (1:1000; Abcam, #ab54210), p19INKD (1:1000; Abcam, #ab80), and H4K16ac (1:2000; Millipore, #07-32) diluted in PBS–5% BSA. The membrane was then incubated with

(16) The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse ModelCancer ResearchMay 1, 2021John R. Jeffers et al.were detected by Western blot analysis using the following primary antibodies: p53 (1C12); p19Arf (ab80; ABCAM).

(17) Pharmacological inactivation of CDK2 inhibits MYC/BCL-XL-driven leukemia in vivo through induction of cellular senescenceCell CycleJanuary 2, 2021Wesam Bazzar, Matteo Bocci, Eduar Hejll, Vedrana Högqvist Tabor, Per Hydbring, Alf Grandien, Mohammad Alzrigat, Lars-Gunnar Larssondeveloped with chemiluminescent HRP substrate. Antibodies used for immunoblotting were anti-p19ARF (ab80, Abcam), anti-p21CIP1 (sc-397, Santa Cruz), anti-Rb (558385, BD Pharmingen), cyclin A1 (sc-239, Santa Cruz

(18) p19Arf Exacerbates Cigarette Smoke-Induced Pulmonary DysfunctionBiomoleculesMarch 17, 2020Ryuta Mikawa, Tadashi Sato, Yohei Suzuki, Hario Baskoro, Koichiro Kawaguchi, Masataka SugimotoThe section were immunostained with rabbit polyclonal antibody against p19Arf (1:200 dilution, cat# ab80, Abcam, Cambridge, UK), rat monoclonal antibody against p19Arf (1:100 dilution, cat# sc-32748, Santa Cruz Biotechnology

(19) Collaboration of MYC and RUNX2 in lymphoma simulates T‐cell receptor signaling and attenuates p53 pathway activityJournal of Cellular BiochemistryOctober 1, 2019Jodie Hay, Kathryn Gilroy, Camille Huser, Anna Kilbey, Alma Mcdonald, Amanda MacCallum, Ailsa Holroyd, Ewan Cameron, James C. Neilα‐p21WAF1, α‐actin (sc‐1207, sc‐471, and sc‐1616, respectively; Santa Cruz Biotechnology), α‐p19ARF (ab80; Abcam), α‐p53 and α‐SMYD2 (IC12 and D14H7, respectively; Cell Signaling Technology). Western blots

(20) Sprouty1 Controls Genitourinary Development via its N-Terminal TyrosineJournal of the American Society of Nephrology : JASNAugust 1, 2019Vaquero M, Cuesta S, Anerillas C, Altés G, Ribera J, Basson MA, Licht JD, Egea J, Encinas M.(catalog no. sc-126; Santa Cruz), anti-p21Cip1 (catalog no. 05–345; Millipore), antip19Arf (catalog no. ab80; Abcam), and anti-Spry2 (catalog no. S1444; Sigma). following the manufacturer’s instructions. Antibodies

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3/14/2016Great p19 Antibody A MOur lab works with a number of different cell cycle regulator proteins in the context of several different types of cancer. We purchased this antibody from Abcam on the recommendation of another lab, ... Read Review

Anti-CDKN2A/p19ARF antibody from Abcam

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Anti-CDKN2A/p19ARF antibody from Abcam

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