Fig 2: Effects of FSGD on PI3K/AKT pathway by immunohistochemistry. (A) The immunohistochemistry staining of PI3K/AKT pathway. (B–E) Image-Pro Plus software was used to statistically analyze the immunohistochemical staining results of PTEN, PI3K, AKT and p-AKT, respectively. The data are expressed as: compared with the normal group; *p < 0.05, **p < 0.01; versus normal group; ## p < 0.01, # p < 0.05, compared with the model group, respectively.