Fig 1: (A) Scatter plot illustration shows a strong positive correlation between endoplasmic reticulum aminopeptidase (ERAP)1 and ERAP2 placental protein expression (r = 0.70; P < 0.0001); (B) box plots of ERAP1/ERAP2 ratios in first trimester tissue (n = 12), normotensive control (NC; n = 12), and pre-eclampsia (PE; n = 12). Data are presented as median [interquartile range (IQR)]; *P < 0.05; ***P < 0.0001.