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Antibodies
Antibodies
Anti-Cleaved PARP1 antibody
Anti-Cleaved PARP1 antibody from Abcam
Be the first to write a review!
Citations:
(48)
Supplier Page
Supplier Page from
Abcam for
Anti-Cleaved PARP1 antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-Cleaved PARP1 antibody
Company
Abcam
Price
Supplier Page
View Company Product Page
Catalog Number
ab4830
Antibody Type
Primary
Quantity
50 UL
Host
Rabbit
Applications
Immunocytochemistry, Western blot
Isotype
IgG
Clonality
Polyclonal
Conjugate/Tag
Unconjugated
Format
Purified from rabbit serum by sequential epitope-specific chromatography. The antibody has been negatively preadsorbed using a peptide spanning the cleavage site to remove antibody that is reactive with full length PARP. The final product is generated by affinity chromatography using a peptide corresponding to the PARP cleavage site
Research Area
Epigenetics
Gene Name
PARP1
Reactivity
Human, Recombinant fragment
Target
Cleaved PARP1
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (48)
(21)
Bufalin suppresses hepatocarcinogenesis by targeting β-catenin/TCF signaling via cell cycle-related kinase
Scientific Reports
December 1, 2018
Zhuo Yu et al.
Cat#
ab49822
;
1:1000
), rabbit anti-
PARP
(
Abcam
, Cat#
ab227244
;
1:2000
), rabbit
anti-cleaved PARP
(
Abcam
, Cat#
ab4830
;
1:1000
), rabbit anti-CDC25A (cell signaling, Cat#ab3652;
1:1000
), rabbit anti-CDK6 (
Abcam
, Cat#
ab151247
;
(22)
PTEN inhibits non‑small cell lung cancer cell growth by promoting G0/G1 arrest and cell apoptosis
Oncology Letters
November 16, 2018
Libao Liu, Lei Huang, Jinyuan He, Songwang Cai, Yimin Weng, Shaohong Huang, Shaohong Ma
Cell Signaling Technology
, Inc. (Danvers, MA, USA). Rabbit polyclonal
anti‑cleaved PARP
antibody (cat. no.
ab4830
) was obtained from
Abcam
and
mouse
monoclonal anti‑ β ‑Actin antibody (cat. no.
sc‑47778
) was purchased
(23)
MORC2, a novel oncogene, is upregulated in liver cancer and contributes to proliferation, metastasis and chemoresistance
International journal of oncology
July 1, 2018
Pan Z, Ding Q, Guo Q, Guo Y, Wu L, Wu L, Tang M, Yu H, Zhou F.
caspase-9
(
1:150
,
sc-56076
;
Santa Cruz Biotechnology, Inc
.), poly (ADP-ribose) polymerase (PARP) (
1:150
,
ab4830
;
Abcam
), p53 (
1:500
,
sc-6243
),
B-cell lymphoma
-2 (Bcl-2) (
1:500
,
sc-783
), Bcl-2-associated X protein
(24)
Calycosin regulates glucocorticoid-induced apoptosis via Nrf2/ARE signaling in MC3T3-E1 cells
Tropical Journal of Pharmaceutical Research
March 6, 2018
Lifeng Fu, WeiLiang Wu, Jian Zhu, Shu Qiang, Jansong Chen
and -9 (
1:1000
; catalog nos.
ab2171
,
ab25901
and
ab52298
;
Abcam
, UK), anti- PARP (
1:1000
; catalog no.
ab4830
;
Abcam
, UK), anti-
Nrf2
(
1:1000
; catalog no.
PA5-19830
;
Invitrogen
, USA), anti-HO1 (
1:1000
; catalog no.
MA1-112
;
(25)
Tegillarca granosa extract Haishengsu inhibits tumor activity via a mitochondrial‑mediated apoptotic pathway
Molecular Medicine Reports
March 1, 2018
Xue‑Hong Chen, Yan‑Tao Han, Jun‑Li Ye, Zhi‑Shang Chang, Chun‑Bo Wang, Shou‑Guo Chen
(Bax;
1:1,000
), cytochrome c, cytochromecoxidase (COX)‑IV (
1:100
), α‑tubulin (
1:5,000
), (cat. nos.
ab4830
,
ab32539
,
ab4051
,
ab59348
,
ab32503
,
ab14744
and
ab7291
respectively;
Abcam
). A rabbit polyclonal antibody
(26)
APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer
Oncotarget
February 20, 2018
Caroline K. Søgaard, Siver A. Moestue, Morten B. Rye, Jana Kim, Anala Nepal, Nina-Beate Liabakk, Siri Bachke, Tone F. Bathen, Marit Otterlei, Deborah K. Hill
Thr389,
Cell Signaling Technology
, #
9206
, MA, USA),
p38
(
Abcam
,
ab31828
, UK), cleaved PARP (
Abcam
,
ab4830
, UK),
Caspase 3
(
Cell Signaling Technology
, #
9662
, MA, USA), β-tubulin (
Abcam
,
ab6046
, UK) and β-actin
(27)
Liquiritin induces apoptosis and autophagy in cisplatin (DDP)-resistant gastric cancer cells in vitro and xenograft nude mice in vivo
International Journal of Oncology
November 1, 2017
Feng Wei, Xin Jiang, Hao-Yue Gao, Shuo-Hui Gao
(
1:500
, KD1406, Santa Cruz Biotechnology),
caspase-3
(
1:1,000
,
ab52293
,
Abcam
), and PARP (
1:1,000
,
ab4830
,
Abcam
) were included. Animals and treatments Forty, 5-week-old male BALB/c-nu
mice
, weighed 15–18
(28)
Hesperitin enhances the ability of daunorubicin by co-loading with MPEG-PCL nanoparticles to induce apoptosis in gastric cancer
Oncotarget
October 31, 2017
Lin-Lin Zhen et al.
Abcam
, USA),
p27
(
ab212252
,
1:1000
,
Abcam
, USA), Caspase-3 (
ab2302
,
1:1000
,
Abcam
, USA), and PARP (
ab4830
,
1:1000
,
Abcam
, USA) were employed. Assessment of anti-
cancer
effects in vivo 40 male, 5 weeks old,
(29)
Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition
Oncotarget
September 22, 2017
Aurélia Nguyen et al.
(30)
The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo
Journal of cellular and molecular medicine
July 1, 2017
Jostes S, Nettersheim D, Fellermeyer M, Schneider S, Hafezi F, Honecker F, Schumacher V, Geyer M, Kristiansen G, Schorle H.
analysis
BRD2
,
Sigma‐Aldrich
,Rabbit,
1:300
,
HPA042816
BRD3,
Abcam
,
Mouse
,
1:50
,
ab50818
BRD4,Active Motif,Rabbit,
1:200
,39909 Cleaved PARP,Abcam,Rabbit,
1:500
,
ab4830
GDF3,
Abcam
,Rabbit,
1:500
,
ab38547
HDAC‐1,
Santa Cruz
,
Mouse
,
1:500
,
sc81598
LIN28,R&D,
Goat
,
1:1000
,AF3757
MYC
,
Cell Signaling
(31)
Mir-30d suppresses cell proliferation of colon cancer cells by inhibiting cell autophagy and promoting cell apoptosis
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
June 1, 2017
Zhang R, Xu J, Zhao J, Bai J.
116kDa, which is purchased from
Cell Signaling Technology
(Danvers, MA, USA).
Anti-Cleaved PARP
antibody (
ab4830
) is a rabbit polyclonal cleaved
PARP
and was purchased from
Abcam
.
ATG5
antibody (Cat. No.
NB110-53818
)
(32)
A signaling cascade including ARID1A, GADD45B and DUSP1 induces apoptosis and affects the cell cycle of germ cell cancers after romidepsin treatment
Oncotarget
November 15, 2016
Nettersheim D, Jostes S, Fabry M, Honecker F, Schumacher V, Kirfel J, Kristiansen G, Schorle H.
12354
,
1:500
Beta-Actin,
Sigma-Aldrich
,AC-15,
1:20000
CDKN1A,
Santa Cruz
,C-19 /
sc-397
,
1:500
cleaved PARP,
Abcam
,
ab4830
,
1:500
GADD45B
,
Sigma-Aldrich
,
AV48346
,
1:1000
H3 pan-acetylation,
Active motif
,
39139
,
1:500
H4 pan-acetylation,
Active motif
(33)
AP1 transcription factors are required to maintain the peripheral taste system
Cell Death & Disease
October 1, 2016
Jayasha Shandilya, Yankun Gao, Tapan K Nayak, Stefan G E Roberts, Kathryn F Medler
injection
.
Immunohistochemistry
Immunohistochemical
analysis was performed as previously described.58, 68 Antibodies were:
anti-cleaved PARP
(
ab4830
;
1:50
), anti-c-Fos (
ab7963
;
1:50
), anti-c-Jun (
ab31419
;
1:50
), anti-AcH3 (
ab1791
;
1:200
) from
Abcam
(34)
HMGB1 knockdown effectively inhibits the progression of rectal cancer by suppressing HMGB1 expression and promoting apoptosis of rectal cancer cells
Molecular medicine reports
July 1, 2016
Wang Z, Wang X, Li J, Yang C, Xing Z, Chen R, Xu F.
P60709) were obtained from
Abgent
Biotech Co., Ltd. (Suzhou, China), and
anti‑cleaved‑PARP
(cat. no.
ab4830
;
Abcam
, Cambridge, MA, USA). All antibodies were used at a dilution of
1:1,000
. The siRNAs were designed
(35)
Inhibition of KIF14 Suppresses Tumor Cell Growth and Promotes Apoptosis in Human Glioblastoma
Cellular Physiology and Biochemistry
September 25, 2015
Wei Huang, JunYu Wang, Danfeng Zhang, Wen Chen, Lijun Hou, Xiaojun Wu, Yicheng Lu
(36)
Involvement of NF-κB and HSP70 signaling pathways in the apoptosis of MDA-MB-231 cells induced by a prenylated xanthone compound, α-mangostin, from Cratoxylum arborescens
Drug Design, Development and Therapy
November 15, 2014
Mohamed Yousif Ibrahim et al.
purchased from
Santa Cruz Biotechnology Inc
., but Bcl2 (
ab38629
) and Poly (ADP-ribose) polymerase (PARP) (
ab4830
) were purchased from
Abcam
(Cambridge, UK). The
membranes
were then incubated for 1 hour at room temperature
(37)
A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models
Molecular cancer therapeutics
June 1, 2014
Tinggui Yin, Maria J Lallena, Emiko L Kreklau, Kevin R Fales, Santiago Carballares, Raquel Torrres, Graham N Wishart, Rose T Ajamie, Damien M Cronier, Phillip W Iversen, Timothy I Meier, Robert T Foreman, Douglas Zeckner, Sean E Sissons, Bart W Halstead, Aimee B Lin, Gregory P Donoho, Yuewei Qian, Shuyu Li, Song Wu, Amit Aggarwal, Xiang S Ye, James J Starling, Richard B Gaynor, Alfonso de Dios, Jian Du
(38)
α-Mangostin from Cratoxylum arborescens demonstrates apoptogenesis in MCF-7 with regulation of NF-κB and Hsp70 protein modulation in vitro, and tumor reduction in vivo
Drug design, development and therapy
January 1, 2014
Ibrahim MY, Hashim NM, Mohan S, Abdulla MA, Kamalidehghan B, Ghaderian M, Dehghan F, Ali LZ, Arbab IA, Yahayu M,
et al
.
purchased from
Santa Cruz Biotechnology Inc
., but Bcl2 (
ab38629
) and poly (ADP-ribose) polymerase (PARP) (
ab4830
) were purchased from
Abcam plc
(Cambridge, UK). The
membranes
were then incubated for 1 hour at room
(39)
Differential PKA activation and AKAP association determines cell fate in cancer cells
Journal of Molecular Signaling
October 1, 2013
Erik D Hedrick, Ekta Agarwal, Premila D Leiphrakpam, Katie L Haferbier, Michael G Brattain, Sanjib Chowdhury
Cell Signaling Technology
. The PKA RII (#
ab124400
), XIAP (#s
ab21278
;
ab28151
), Praja2 (#s
ab131118
;
ab56876
), PARP (#
ab4830
) and
Smad3
(#
ab28379
) antibodies were purchased from
Abcam
. Anti-Actin antibody was purchased from
(40)
Dual kinase inhibition promotes pluripotency in finite bovine embryonic cell lines
Stem cells and development
June 1, 2013
Vinod Verma, Ben Huang, Prasanna Kumar Kallingappa, Björn Oback
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Reviews
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Anti-Cleaved PARP1 antibody from Abcam
Supplier Page
View Company Product Page
Product Specs
Company Info
Citations
Reviews
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