Fig 2: Association between p-JAK1 expression status and survival time in NSCLC. Kaplan-Meier curves compare the overall survival time of patients with positive (dotted line) or negative (solid line) p-JAK1 expression. Kaplan-Meier curves for (A) all types of NSCLC, (B) adenocarcinoma and (C) squamous cell carcinoma subtypes are illustrated. p-JAK1, phosphorylated Janus kinase 1; NSCLC, non-small cell lung carcinoma.

Fig 3: Association between p-JAK1 expression status and survival time in early and late stage NSCLC. Kaplan-Meier curves for patient survival are stratified by p-JAK1 positive (dotted line) and negative expression (solid line) in (A) Tumor size <3 cm (B) Tumor size =3 cm, (C) N0/1 (D) N2/3 (E) stage I/II and (F) stage III/IV groups, respectively. p-JAK1, phosphorylated Janus kinase 1; NSCLC, non-small cell lung carcinoma.

Fig 4: Association between the combination of p-JAK1 expression and EGFR gene duplication, and survival time in patients with lung adenocarcinoma. Kaplan-Meier curves for patient survival are stratified by p-JAK1 positive or negative expression with EGFR duplication positive or negative status. Solid line, p-JAK1-/EGFR- expression; dashed line, p-JAK1-/EGFR+; half-dotted line, p-JAK1+/EGFR-, dotted line, p-JAK1+/EGFR+. p-JAK1, phosphorylated Janus kinase 1; EGFR, epidermal growth factor receptor.