Fig 1: Testicular gene expression of (A) NF-?B, (B) TNF-a and tissue levels of (C) IL1-ß and (D) IL-6 in the normal control (NC) group and experimental groups (MTX, crude extract + MTX, zygo-albuside A + MTX, rutin + MTX). Statistical analysis was performed using ANOVA followed by Tukey’s post hoc test. Values are expressed as mean ± SD (n = 8). A statistically significant difference was assumed at p < 0.01 and denoted by * vs. NC; # vs. MTX. NF-?B; nuclear factor kappa B, TNF-a; tumor necrosis factor-a, IL-1ß; interleukin-1ß, IL-6; interleukin-6.
Fig 2: Effect of M. alysson L. methanolic extract, its polyphenolic fraction, kaempferol, quercetin and rutin on testicular injury-induced mice. (A) Testicular NF-?B mRNA expression, (B) Testicular TNF-a mRNA expression, (C) Testicular IL-1ß level and (D) Testicular IL-6 level. Data are presented as mean ± SD, (n = 8). * Significant versus normal control. # Significant versus MTX. ^ Significant versus methanolic extract. $ Significant versus polyphenolic fraction. p value = 0.01.
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