Fig 1: Oxidative stress parameters (MDA, GPx and SOD) levels in different experimental groups. Data were presented as mean ± SEM, *represented a significance difference in comparison to diabetic untreated subgroup DGI and #represented a significance difference in comparison to healthy control subgroup HGI at p < 0.05 by One Way ANOVA and Tukey post hoc test (n = 6). HGI Control untreated rats, HGII Healthy rats that received free Mel (5 mg/kg), HGIII Healthy rats that received free Mel (10 mg/kg), HGIV Healthy rats that received unloaded C/L nanoparticles (5 mg/kg), HGV Healthy rats that received unloaded C/L nanoparticles (10 mg/kg), HGVI Healthy rats that received Mel-C/L nanoparticles (5 mg/kg), HGVII Healthy rats that received Mel-C/L nanoparticles (10 mg/kg), DGI Control untreated rats, DGII Diabetic rats that received free Mel (5 mg/kg), DGIII Diabetic rats that received free Mel (10 mg/kg), DGIV Diabetic rats that received unloaded C/L nanoparticles (5 mg/kg), DGV Diabetic rats that received unloaded C/L nanoparticles (10 mg/kg), DGVI Diabetic rats that received Mel-C/L nanoparticles (5 mg/kg), DGVII Diabetic rats that received Mel-C/L nanoparticles (10 mg/kg).
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