Fig 1: Effects of EPO overexpression on the serum levels of inflammatory mediators in rats that underwent AAC. ELISA was employed to determine the levels of inflammatory mediators (A) TGF-ß1, (B) TNF-a, (C) IL-1ß, (D) IL-6 and (E) IL-17A in the rat serum in each group. The data are expressed as the mean ± standard error of the mean (n=6 per group). *P<0.05 vs. the control group; #P<0.05 vs. the AAC only group; and &P<0.05 vs. the AAC + EPO group. EPO, erythropoietin; AAC, abdominal aortic constriction; TGF, transforming growth factor; TNF, tumor necrosis factor; IL, interkleukin; TLR4, Toll-like receptor 4.
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