Fig 1: Correlation between plasma levels of CTHRC1 and notable clinical measures in all subjects (Control + CKD groups). The relationship between variables was evaluated using Pearson’s correlation test. Trend lines indicate linear correlation. Pearson’s (r) coefficient and the corresponding p-values are shown on each plot. Scatter plot graphs illustrating correlation between (A) CTHRC1 and uric acid, (B) CTHRC1 and total protein collected in 24 h in urine, (C) CTHRC1 and cholesterol, (D) CTHRC1 and urea, (E) CTHRC1 and plasma total protein levels, (F) CTHRC1 and creatinine, (G) CTHRC1 and ionized calcium levels.
Fig 2: ROC curve and AUC for CTHRC1 levels and other markers in patients with eGFR rates below 60 mL/min/1.73 m2 (eGFR < 60) and above 60 mL/min/1.73 m2 (eGFR > 60). Cut-off values were defined as the value whose sensitivity and specificity are the closest to the value of the area under the ROC curve. * Area under ROC curve lies with 95% confidence interval.
Fig 3: Correlation between plasma levels of CTHRC1 and notable clinical measures in CKD patients. The relationship between variables was evaluated using Pearson’s correlation test. Trend lines indicate linear correlation. Pearson’s (r) coefficient and the corresponding p-values are shown on each plot. Scatter plot graphs illustrating correlation between (A) CTHRC1 and uric acid, (B) CTHRC1 and total protein collected in 24 h in urine, (C) CTHRC1 and cholesterol, (D) CTHRC1 and urea, (E) CTHRC1 and plasma total protein levels, (F) CTHRC1 and creatinine (CTHRC1 and creatinine parameters were analyzed via Spearman’s rank correlation test), (G) CTHRC1 and ionized calcium levels, (H) CTHRC1 and eGFR.
Fig 4: ROC curve and AUC for CTHRC1 levels and other markers in patients with eGFR rates below 60 mL/min/1.73 m2 (eGFR < 60). Cut-off values were defined as the value whose sensitivity and specificity are the closest to the value of the area under the ROC curve. * Area under ROC curve lies with 95% confidence interval.
Fig 5: Significant differences in CTHRC1 between control group and CKD patients. Unpaired two-tailed t-test was used to calculate the p values to define the significance. **** p = 0.0001.
Supplier Page from Abcam for Human CTHRC1 ELISA Kit