Fig 2: Deletion of GSK3ß inhibits MI/R injury: (a) Western blot analysis was used to detect the protein expression of GSK3ß in the myocardial tissue of GSK3ß WT mice and GSK3ß CKO mice; (b) M-mode echocardiogram images of GSK3ß WT mice and GSK3ß CKO mice; (c) TTC staining statistics of myocardial tissue sections of GSK3ß WT mice and GSK3ß CKO mice; (d) HE staining of myocardial tissue of GSK3ß WT mice and GSK3ß CKO mice; (e) statistics of the expression of LDH, CK, CK-MB, cTnI, and BNP in the peripheral blood of GSK3ß WT mice and GSK3ß CKO mice; (f) TUNEL detected the apoptosis of cardiomyocytes in GSK3ß WT mice and GSK3ß CKO mice; the scale bar was 25 µm; (g) detection of Caspase-3 activity in the myocardial tissue of GSK3ß WT mice and GSK3ß CKO mice; (h) DCF-DA staining of the myocardial tissue section of GSK3ß WT mice and GSK3ß CKO mice to detect the expression of ROS in the cells; (i) the activity of SOD and the content of MDA in the hearts of GSK3ß WT mice and GSK3ß CKO mice. N = 8. Measurement data were expressed as the mean ± standard deviation. Data in compliance with normal distribution and homogeneity of variance between two groups were compared using unpaired t-test.