Fig 1: The Proposed Mechanism of the Prepared Polyherbal Syrup on PCOS. AMPK- adenosine5'monophosphate-activated protein kinase, AR- androgen receptor, Akt-serine/threonine-specific protein kinase, DHEA-dehydroepiandrosterone, FSH- follicle-stimulating hormone, GLUT4-glucose transporter 4, GnRH-gonadotropin releasing hormone, IGF-1- insulin-like growth factor-1, IGFBP-1- insulin-like growth factor binding protein-1, INSR-insulin receptor, IR-insulin resistance, IRS-insulin receptor substrate, LH- luteinizing hormone, PHS- polyherbal syrup, PI3K- phosphatidylinositol 3-kinase, SHBG-sex hormone-binding globulin, TC- total cholesterol, TG-triglyceride, 3ß-HSD - 3ß-hydroxyl steroid dehydrogenase, 17ß-HSD- 173ß-hydroxyl steroid dehydrogenase. PHS + = stimulation/increase, PHS - = inhibition/decrease, Image 1 = positive influence, Image 2 = inhibition influence on pathogenic pathway, Image 3 = positive influence, Image 4 = inhibition influence on therapy pathway.
Supplier Page from Thermo Fisher Scientific for Human SHBG ELISA Kit