Fig 1: Box plots; a No significant differences were revealed in calpain2 measures between AD and controls nor between WML and NAWM measures within groups. No significant differences were revealed in MAG:PLP measures between AD and controls nor between WML and NAWM measures within groups. p values are shown in main text. AD, Alzheimer’s disease; MAG, myelin-associated glycoprotein; PLP, proteolipid protein
Fig 2: Box plots show; a Calpain2 was significantly higher in the WML tissue of AD cases compared to controls. b No significant difference was seen in WML-MAG between AD and control cases. c PLP was significantly lower in the WML tissue of AD cases compared to controls. d MAG:PLP was significantly lower in the WML tissue of control compared to AD cases. *p < 0.05; ***p < 0.001. Exact p values are shown in main text. AD Alzheimer’s disease, MAG myelin associated glycoprotein, PLP proteolipid protein
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